Short and Long Term Outcomes of Acute Coronary Syndrome in Patients With Non Obstructive Coronary Atherosclerosis
NOCA
1 other identifier
interventional
200
1 country
1
Brief Summary
The purpose of the study is to assess short and long term outcomes of acute coronary syndrome in patients with non obstructive coronary atherosclerosis, to optimize the algorithm for diagnosis and to evaluate its effectiveness
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Oct 2015
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2015
CompletedFirst Submitted
Initial submission to the registry
December 29, 2015
CompletedFirst Posted
Study publicly available on registry
January 14, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2018
CompletedJanuary 14, 2016
January 1, 2016
2.9 years
December 29, 2015
January 13, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Incidence of inflammatory infiltrate, ischemia, infarction in the myocardial tissue
14 days after ACS
Left ventricular ejection fraction (Echo)
14 days after ACS
Secondary Outcomes (8)
Incidence of the acute myocardial infarction
14 days after ACS
Incidence of unstable angina
14 days after ACS
Incidence of Takotsubo syndrome
14 days after ACS
Incidence of myocarditis
14 days after ACS
Incidence of the mortality
6 month and 12 month after ACS
- +3 more secondary outcomes
Study Arms (1)
Patients with ACS
OTHERPatients with ACS who underwent coronary angiography within 72 hours from the onset of disease. In identifying nonobstructive coronary atherosclerosis , patients underwent cardiac contrast MRI.
Interventions
Cardiovascular magnetic resonance (CMR) imaging with contrast (Gadovist) in regime inversion recovery time, regime T-2 weighted images , T1-weighted images.
Eligibility Criteria
You may qualify if:
- age ≥ 18 years at time of randomization (18 years and older)
- acute coronary syndrome
- no obstructive coronary atherosclerosis (normal coronary artety/ plaques \<50%) is based on the results of coronary angiography for 3 days of admission
- written the informed consent to participate in research
You may not qualify if:
- patients previously undergone endovascular / surgical revascularization of coronary artery
- severe comorbidity
- Contacts/Locations
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Research Institutite for Cardiology
Tomsk, Tomskii Region, 634012, Russia
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Vyacheslav Ryabov, MD,PhD
Research Institute for Cardiology
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- MD, PhD Research Institute for Cardiology
Study Record Dates
First Submitted
December 29, 2015
First Posted
January 14, 2016
Study Start
October 1, 2015
Primary Completion
September 1, 2018
Study Completion
September 1, 2018
Last Updated
January 14, 2016
Record last verified: 2016-01