Retroclavicular Versus Supraclavicular Brachial Plexus Block for Hand and Forearm Surgery
The Efficacy of Retroclavicular Versus Supraclavicular Brachial Plexus Block in Patients Undergoing Forearm and Hand Surgery: a Randomized Controlled Double-blinded Trial.
1 other identifier
interventional
120
1 country
1
Brief Summary
Patients will be randomized to one of two groups:
- 1.Supraclavicular group: supraclavicular brachial plexus block performed with the aid of ultrasound;
- 2.Retroclavicular group: retroclavicular brachial plexus block performed with the aid of ultrasound.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for phase_4
Started Jan 2016
Typical duration for phase_4
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 1, 2015
CompletedFirst Posted
Study publicly available on registry
December 29, 2015
CompletedStudy Start
First participant enrolled
January 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2018
CompletedMay 9, 2018
May 1, 2018
2.3 years
December 1, 2015
May 8, 2018
Conditions
Outcome Measures
Primary Outcomes (1)
Success rate (loss of sensation to pinprick in the forearm and hand)
30 minutes after the injection
Secondary Outcomes (7)
Needling time in seconds
15 min
Time to first analgesic request
24 hours
Block-related complications
24 hours
Postoperative opioid consumption on postoperative day 1
24 hours
Pain scores at 12 hours postoperatively
12 hours
- +2 more secondary outcomes
Study Arms (2)
supraclavicular
ACTIVE COMPARATORpatients receive a supraclavicular block for forearm or hand surgery with 30 ml of a mixture of ropivacaine 0.5 % and mepivacaine 1 %
retroclavicular block
EXPERIMENTALpatients receive a retroclavicular block for forearm or hand surgery with 30 ml of a mixture of ropivacaine 0.5 % and mepivacaine 1 %
Interventions
retroclavicular block for forearm or hand surgery
Eligibility Criteria
You may qualify if:
- Adult patients who undergo forearm or hand surgery under brachial plexus block.
You may not qualify if:
- History of allergic reaction to local anaesthetics
- Peripheral neuropathy
- Renal or hepatic insufficiency
- Coagulation disorders
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hopital du Valais
Sion, 1950, Switzerland
Related Publications (1)
Grape S, Pawa A, Weber E, Albrecht E. Retroclavicular vs supraclavicular brachial plexus block for distal upper limb surgery: a randomised, controlled, single-blinded trial. Br J Anaesth. 2019 Apr;122(4):518-524. doi: 10.1016/j.bja.2018.12.022. Epub 2019 Jan 31.
PMID: 30857608DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Sina Grape, MD
Hopital du Valais
- STUDY DIRECTOR
Eric Albrecht, MD
CHUV
Study Design
- Study Type
- interventional
- Phase
- phase 4
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- MD
Study Record Dates
First Submitted
December 1, 2015
First Posted
December 29, 2015
Study Start
January 1, 2016
Primary Completion
May 1, 2018
Study Completion
May 1, 2018
Last Updated
May 9, 2018
Record last verified: 2018-05