NCT02639845

Brief Summary

The purpose of this study is to determine if an eye drop video monitoring device can accurately assess (as compared to a patient's own log or a proprietary software) the exact amount and time of eye drop delivery to a patient's eye. It is our belief that the experimental device will help patients to be more compliant by: 1) providing a viewable format so patients can see what is happening when they are applying their drops 2) providing greater accuracy to doctors regarding when and how much medication was used 3) providing greater accuracy to doctors and patients regarding how much medication was actually delivered to a patients eye.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2013

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2013

Completed
2.1 years until next milestone

First Submitted

Initial submission to the registry

December 18, 2015

Completed
10 days until next milestone

First Posted

Study publicly available on registry

December 28, 2015

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2016

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2017

Completed
Last Updated

December 28, 2015

Status Verified

December 1, 2015

Enrollment Period

3.1 years

First QC Date

December 18, 2015

Last Update Submit

December 24, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Variation from a Prescribed Ophthalmic Drop Regimen

    The Eye Drop Application Monitor will be brought to the reading center based at Retina Health Center (Fort Myers, FL) at the end of each use. A trained technician will then document the time of drop delivery and how many drops got in the eye.

    Up to four weeks of monitoring beginning immediately after eye drops are prescribed

Study Arms (1)

Patients Prescribed Eye Drops

Patients who are scheduled to receive prescription eye drops due to complications such as cataract surgery, glaucoma, retina surgery, or eye-related condition.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients who are scheduled to receive prescription eye drops, one of which must be applied at least once a day.

You may qualify if:

  • Patients who are scheduled to receive prescription eye drops
  • Eye drop(s) must be applied at least once a day.
  • Caregivers who apply drops for patients

You may not qualify if:

  • Children (patients \< 18 years old)
  • Those unable to self-consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Retina Health Center

Fort Myers, Florida, 33907, United States

RECRUITING

Related Publications (1)

  • Eaton AM, Gordon GM, Konowal A, Allen A, Allen M, Sgarlata A, Gao G, Wafapoor H, Avery RL. A novel eye drop application monitor to assess patient compliance with a prescribed regimen: a pilot study. Eye (Lond). 2015 Oct;29(10):1383-91. doi: 10.1038/eye.2015.155. Epub 2015 Sep 11.

MeSH Terms

Conditions

CataractGlaucoma

Condition Hierarchy (Ancestors)

Lens DiseasesEye DiseasesOcular Hypertension

Study Officials

  • Soratree Charoenthongtrakul, Ph.D.

    Retina Health Center

    STUDY DIRECTOR

Central Study Contacts

Soratree Charoenthongtrakul, Ph.D.

CONTACT

Alexander M Eaton, M.D.

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Managing Partner

Study Record Dates

First Submitted

December 18, 2015

First Posted

December 28, 2015

Study Start

November 1, 2013

Primary Completion

December 1, 2016

Study Completion

June 1, 2017

Last Updated

December 28, 2015

Record last verified: 2015-12

Locations