Food Addiction and Hormone Study

NCT02638155 | Completed

• 1 other identifier: 505490
• Study Type: observational
• Target: 23
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this exploratory study is to use Electrogastrography (EGG) to measure and compare the gastric myoelectrical activity between persons with food addiction (FA) and a control group. Additionally, this study will explore if differences exist between perceived hunger and satiety and hormone levels related to hunger and satiety in both groups. The comparison of the EGG readings and hormone levels is the next step in furthering our understanding of food addiction and how the physiology - not simply the symptomatology - of FA does or does not relate to weight management.

Conditions

Disordered Eating

Outcome Measures

Primary Outcomes (1)

• Electrogastrography (EGG) using Bipoac Systems EGG machine

  Skin electrode similar to EKG attached to abdomen and readings taken

  the participant will be tested continuously for approximately 3 1/2 hours on 1 day, readings are collected on a PC

Secondary Outcomes (14)

• Ghrelin

  collected via IV catheter over approximately 3 1/2 hours on one day

• Peptide YY

  collected via IV catheter over approximately 3 1/2 hours on one day

• GLP-1

  collected via IV catheter over approximately 3 1/2 hours on one day

• Insulin

  collected via IV catheter over approximately 3 1/2 hours on one day

• Glucose

  collected via IV catheter over approximately 3 1/2 hours on one day

Study Arms (2)

Food Addiction Group

Those participants identified as having food addiction by the Yale Food Addiction Scale.

No Food Addiction Group

Those participants with no identified food addiction

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

men and women 18-65 who are able to come to TTU for testing and meet eligibility criteria

You may qualify if:

• Participants will include men and women who identify with weight struggles related to disordered eating and a control sample of people who do not identify with weight issues or disordered eating. Must be able to read and write English

You may not qualify if:

• Anyone with a chronic disease including type II diabetes, hypothyroidism, hypoparathyroidism, cardiovascular disease, cancer of any type
• Anyone who is currently pregnant, or lactating
• Medications that may influence or inhibit appetite, sensory functioning, or hormone signaling- e.g. antibiotics, anti-depressants, obesity medications
• Report of medical condition or surgical intervention that affects swallowing ability
• Allergy, aversion, or dislike to any of the meal replacements or snacks offered
• Previous or current diagnosis of a psychiatric illness such as schizophrenia or any other psychotic disorder listed in the DSM-IV or DSM-5
• Report of medical conditions that prohibits overnight fasting

Sponsors & Collaborators

• Texas Tech University: lead

Study Sites (1)

TTU College of Human Sciences

Lubbock, Texas, 79409, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

Blood

Study Officials

• Cynthia Dsauza, PhD

  Assistant Professor

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: December 3, 2015
• First Posted: December 23, 2015
• Study Start: August 1, 2016
• Primary Completion: November 11, 2016
• Study Completion: November 11, 2016
• Last Updated: April 1, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)