NCT02632968

Brief Summary

Pinhole surgical technique is a novel minimally invasive, predictable, efficient, time and cost-effective technique for treatment of multiple gingival recession. This procedure involves no releasing incision, suturing or sharp dissections. It has been shown that the greater post-operative displacement of gingival margin may cause greater root coverage. Based on this hypothesis, a split mouth randomized controlled clinical trial was planned to compare the clinical outcome of pinhole surgical technique with and without the use of orthodontic buttons and sutures in the treatment of multiple gingival recessions.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
80

participants targeted

Target at P25-P50 for phase_4

Timeline
Completed

Started Nov 2013

Typical duration for phase_4

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2013

Completed
2.1 years until next milestone

First Submitted

Initial submission to the registry

December 15, 2015

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 17, 2015

Completed
15 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2016

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2016

Completed
Last Updated

December 17, 2015

Status Verified

December 1, 2015

Enrollment Period

2.2 years

First QC Date

December 15, 2015

Last Update Submit

December 15, 2015

Conditions

Outcome Measures

Primary Outcomes (4)

  • Percentage of Mean Root Coverage

    6 months

  • Complete Root Coverage

    6 months

  • Root Coverage Esthetic Score

    6 months

  • Recession Depth Reduction

    6 months

Secondary Outcomes (7)

  • Gingival Recession Width Reduction

    6 months

  • Probing Depth (PD)

    6 months

  • Clinical Attachment Level (CAL)

    6 months

  • Keratinized Tissue Width (KTW)

    6 months

  • Bleeding Index (BI)

    6 months

  • +2 more secondary outcomes

Study Arms (2)

Pinhole surgery with orthodontic buttons

ACTIVE COMPARATOR

Pinhole surgery with orthodontic buttons The selected participants were assigned in test and control. In the test group orthodontic buttons were cemented on the bid-buccal region of the crown with dual cure GIC. After administration of LA, 2 to 3 pinhole incisions were made and a full thickness muco-periosteal tunnel was raised and collagen membrane was tucked in through the pinhole incisions. The sling sutures 5-0 mersilk were placed to hold the tunnel in an advanced location using orthodontic buttons as anchoring units. Inter-dental sutures with 6-0 mersilk were also placed for stabilization of the advanced gingival tissue.

Procedure: Pinhole surgery with and without buttons

Pinhole surgery without buttons

ACTIVE COMPARATOR

Pinhole surgery without orthodontic buttons The selected participants were assigned in test and control. In the control group, after administration of LA, 2 to 3 pinhole incisions were made and a full thickness muco-periosteal tunnel was raised and collagen membrane was tucked in through the pinhole incisions till the recession defects were covered. No sutures or orthodontic buttons were used in the control site.

Procedure: Pinhole surgery with and without buttons

Interventions

Pinhole surgery with orthodontic buttonsPinhole surgery without buttons

Eligibility Criteria

Age25 Years - 55 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Multiple (atleast two or three) Millers class I and II or combined class I and II recession defects18 affecting adjacent teeth of the maxillary arch.
  • Patients with thick gingival biotypes \>0.8mm.
  • Presence of adequate keratinized tissue apical to recession \> 1mm.
  • Age group 25-55 years.
  • Patients with history of compliance to oral hygiene instructions and a full mouth plaque score of \<10%.
  • Patients willing to participate in the study.
  • American Society of Anaesthesiologists Physical Status I or II.
  • No contra-indications for periodontal surgery.
  • Non-Smokers.
  • Patients with esthetic concerns.

You may not qualify if:

  • Recession defects associated with caries/demineralization, restorations, and deep abrasions (step \>2mm).
  • No occlusal interferences.
  • Teeth with evidence of pulpal pathology.
  • Patients who have undergone any previous periodontal surgical procedures at the involved sites.
  • Pregnant and lactating women.
  • Patients on medications known to interfere with periodontal tissue health or healing.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Krishnadevaraya College of Dental Sciences and Hospital

Bangalore, Karnataka, 562157, India

RECRUITING

MeSH Terms

Conditions

Gingival Recession

Condition Hierarchy (Ancestors)

Gingival DiseasesPeriodontal DiseasesMouth DiseasesStomatognathic DiseasesPeriodontal Atrophy

Study Officials

  • Dr. Joann P George, MDS

    Krishnadevaraya College of Dental Sciences and Hospital, Krishnadevarayanagara, Hunsamaranahalli, International Airport Road, Bangalore 562157

    STUDY DIRECTOR

Central Study Contacts

Dr. Joann P George, MDS

CONTACT

Dr. Divya Khanna, MDS (BDS)

CONTACT

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 15, 2015

First Posted

December 17, 2015

Study Start

November 1, 2013

Primary Completion

January 1, 2016

Study Completion

March 1, 2016

Last Updated

December 17, 2015

Record last verified: 2015-12

Locations