NCT02632240

Brief Summary

The aim of this study is to compare the efficacy of dental root coverage using the tunnel technique with connective tissue graft (CTG) and the same technique with collagen matrix for treatment of multiple gingival recessions Miller Class I and II. This study is a randomized-controlled clinical trial of 6 months duration.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2014

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2014

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2015

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

December 13, 2015

Completed
3 days until next milestone

First Posted

Study publicly available on registry

December 16, 2015

Completed
Last Updated

December 18, 2015

Status Verified

December 1, 2015

Enrollment Period

6 months

First QC Date

December 13, 2015

Last Update Submit

December 16, 2015

Conditions

Keywords

gingival recessionmucogingival surgerycollagen matrixconnective tissue grafttunnel technique

Outcome Measures

Primary Outcomes (1)

  • Clinical attachment level (CAL)

    Distance from the cemento enamel junction to the deepest point of the gingival sulcus

    6 months

Secondary Outcomes (6)

  • Recession depth (RD)

    6 months

  • Recession width (RW)

    6 months

  • Width of keratinized tissue (KTW)

    6 months

  • Recession area (RA)

    6 months

  • the average percentage of root coverage (ARC)

    6 months

  • +1 more secondary outcomes

Other Outcomes (1)

  • The depth of gingival sulcus (PD)

    6 months

Study Arms (2)

Control group

ACTIVE COMPARATOR

Surgery:The tunnel technique for covering gingival recession. Graft: connective tissue.

Other: Surgery:The tunnel technique for covering gingival recession

Study group

ACTIVE COMPARATOR

Surgery:The tunnel technique for covering gingival recession.Graft: xenogenic collagen matrix (Mucoderm).

Other: Surgery:The tunnel technique for covering gingival recession

Interventions

The surgery starts with the sulcular incisions in the region of recessions, which enable access for the supraperiosteal preparation. The procedure is extended into the mucosal tissue using the tunneling knives. The partial-thickness flap is performed at the buccal site. Only the papillary regions are fully detached with the periosteum. The graft is placed into the tunnel and stabilized with absorbable sutures.The mobilized mucous flap is advanced coronally and stabilized with non-absorbable suspensory sutures.

Control groupStudy group

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Presence of minimum two adjacent periodontal recessions Miller class I or II and at least 2 mm recessions depth.

You may not qualify if:

  • Approximal Plaque Index (API) \> 15%,
  • Sulcus Bleeding Index (SBI) \> 10%,
  • Systemic diseases with compromised healing potential or infectious diseases,
  • Untreated periodontal conditions,
  • Pregnant and lactating females.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Periodontal and Oral Mucosa Diseases

Zabrze, 41-800, Poland

Location

MeSH Terms

Conditions

Gingival Recession

Condition Hierarchy (Ancestors)

Gingival DiseasesPeriodontal DiseasesMouth DiseasesStomatognathic DiseasesPeriodontal Atrophy

Study Officials

  • Marta Tanasiewicz, Professor

    Department of Conservative Dentistry with Endodontics

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PhD DDS

Study Record Dates

First Submitted

December 13, 2015

First Posted

December 16, 2015

Study Start

October 1, 2014

Primary Completion

April 1, 2015

Study Completion

April 1, 2015

Last Updated

December 18, 2015

Record last verified: 2015-12

Locations