Plasticity and Cross-modal Interactions in Profoundly Deaf Adults
PLASMODY
1 other identifier
interventional
17
1 country
1
Brief Summary
The aim of this study is to evaluate cerebral asymmetry for face processing in a group of profoundly deaf participants and a group of hearing controls by the mean of fMRI measure. To this end, we present chimeric faces (faces split into different halves), entire faces, or faces presented in divided visual field, and subjects perform a gender categorization task while lying in a fMRI scanner. It is expected to find a reduced cerebral asymmetry in the Fusiform Face Area in deaf in comparison with hearing participants.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Apr 2014
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2014
CompletedFirst Submitted
Initial submission to the registry
August 11, 2015
CompletedFirst Posted
Study publicly available on registry
December 16, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2016
CompletedJanuary 18, 2017
January 1, 2017
2.7 years
August 11, 2015
January 17, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
cerebral activity (fMRI measure)
Time 0
Study Arms (3)
Deaf
EXPERIMENTALGroup of early profound deaf participants fMRI measure
Hearing signers
EXPERIMENTALGroup of hearing signer controls fMRI measure
Hearing non signers
SHAM COMPARATORGroup of hearing non signer controls fMRI measure
Interventions
Eligibility Criteria
You may qualify if:
- Consent Form signed
- Medical exam performed before entering in to the scanner
- age between 18 and 60 years
- Absence of neurological and/or psychiatric troubles
- Normal or corrected vision
- Right handed
- For Deaf participants:
- Bilateral hearing loss 80 dB or more
- Hearing loss before 2 years of age
- use of French Sign Language
- For Hearing participants - signers:
- Absence of hearing loss
- Use of French sign Language (Bilingual)
- For Hearing participants - non signers:
- Absence of hearing loss
You may not qualify if:
- Pregnant women, mothers who suckle, minors
- Presence of metal implants (cardiac implants, bone implants, auditory implants...),
- Presence of skin implants: not removable body piercings, tattoos, not removable jewels
- Claustrophobia
- Visual impairment without correction
- Neurological/Psychiatric disorder
- Cardiac or respiratory trouble
- For Deaf participants:
- unilateral hearing loss
- cochlear implant
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
plateforme IRMage
Grenoble, 38000, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- BASIC SCIENCE
- Intervention Model
- FACTORIAL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
August 11, 2015
First Posted
December 16, 2015
Study Start
April 1, 2014
Primary Completion
December 1, 2016
Study Completion
December 1, 2016
Last Updated
January 18, 2017
Record last verified: 2017-01