Oral Hygiene Care and Microflora in Elderly Residents

NCT02627469 | Completed

• 1 other identifier: KarolinskaII
• Study Type: interventional
• Target: 68
• Locations: 0 countries
• Sites: N/A

Brief Summary

Objective: The effect of weekly professional oral care on the composition of the oral flora in dentate, dependent elderly residents was followed during a 12-month period. Background: Long-term, regular professional oral hygiene care reduces the total number of microorganisms and oral disease-related microorganisms. Less is known about the effect on the quality/composition of the remaining oral flora. Materials and methods: Thirty-three subjects were included in the study group and 35 in the control group. Dental status, presence of supragingival-plaque, labial minor gland secretion rate, and prescription medicines were recorded. Microbial samples, collected from supragingival plaque and the dorsum of the tongue, were analyzed using cultivation technique.

Conditions

Pneumonia; Aspiration

Keywords

Microbiota; aged; oral health

Outcome Measures

Primary Outcomes (1)

• Composition of the oral microflora

  Microbial samples were collected from the supragingival plaque and the dorsum of the tongue. The total number of microorganisms growing under anaerobic conditions, the total number and proportion of streptococci, lactobacilli, Actinomyces spp, F. nucleatum, P. intermedia/nigrescens, P. gingivalis, A. actinomycetemcomitans, Candida albicans, Staphylococcus aureus, and enteric rods, were calculated. The detection limit was 100 colony-forming units for all species except A. actinomycetemcomitans, where the detection limit was 10 colony-forming units. If possible, the number of microorganisms was calculated from their number on a plate giving 30 - 300 colonies. A mean of the results from the duplicate samplings was calculated.

  12 months

Secondary Outcomes (3)

• Rate of Labial minor gland salivary secretion

  12 months

• Presence of supragingival-plaque

  12 months

• Dental status

  12 month

Other Outcomes (1)

• Prescription medicines

  12 months

Study Arms (2)

Control

NO INTERVENTION

Common oral hygiene help administered by nursing staff

Intervention

EXPERIMENTAL

Extended professional oral hygiene care Electric toothbrush (Oral-B Professional Care 7000) 1100 ppm sodium fluoride dentifrice (Zendium Classic, Opus Health Care AB/Zendium)

Behavioral: Extended professional oral hygiene care; Device: Electric toothbrush (Oral-B Professional Care 7000); Device: 1100 ppm sodium fluoride dentifrice (Zendium Classic)

Interventions

Extended professional oral hygiene care BEHAVIORAL

Weekly professional oral hygiene performed by dental hygienists

Intervention

Electric toothbrush (Oral-B Professional Care 7000) DEVICE

Weekly professional oral hygiene performed by dental hygienists

Intervention

1100 ppm sodium fluoride dentifrice (Zendium Classic) DEVICE

Weekly professional oral hygiene performed by dental hygienists

Intervention

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)

You may qualify if:

• or more natural teeth
• no removable dentures
• no or mild cognitive impairments

You may not qualify if:

• less than 10 natural teeth
• removable dentures
• severe cognitive impairments

Sponsors & Collaborators

• Karolinska Institutet: lead
• The Swedish Research Council: collaborator

MeSH Terms

Conditions

Pneumonia

Condition Hierarchy (Ancestors)

Respiratory Tract Infections; Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Inger Wårdh, Assoc prof

  Karolinska Institutet

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD Associate professor

Study Record Dates

• First Submitted: November 4, 2015
• First Posted: December 11, 2015
• Study Start: August 1, 2007
• Primary Completion: June 1, 2009
• Study Completion: June 1, 2010
• Last Updated: August 13, 2018

Record last verified: 2018-08

Data Sharing

• IPD Sharing: Will share
• Time Frame: 20180810
• Access Criteria: Public