Trials Sponsors Conditions Drugs Pricing

Conditions

Cerebral Embolism

Outcome Measures

Primary Outcomes (1)

Cerebral Microembolic Load detected by Transcranial Doppler Ultrasound
During hemodialysis therapy

Study Arms (2)

CRRT group

ACTIVE COMPARATOR

the CRRT group receives continuous renal replacement therapy for acute kidney injury

Device: Renal replacement therapy

IRRT group

ACTIVE COMPARATOR

the IRRT group receives intermittent renal replacement therapy after termination of CRRT.

Device: Renal replacement therapy

Interventions

Renal replacement therapyDevice

Patients receive renal replacement therapy according to institutional standards

Also known as: Hemodialysis

CRRT groupIRRT group

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

\> 18 yrs.
Signed IC

You may not qualify if:

Sponsors & Collaborators

Insel Gruppe AG, University Hospital Bern
Otherlead

Study Sites (1)

University Hospital Bern

Bern, 3010, Switzerland

Related Publications (1)

Erdoes G, Uehlinger DE, Kobel B, Stucki MP, Wiest R, Stueber F, Fankhauser N, Jakob SM, Schefold JC. Cerebral microembolism in the critically ill with acute kidney injury (COMET-AKI trial): study protocol for a randomized controlled clinical trial. Trials. 2018 Mar 21;19(1):189. doi: 10.1186/s13063-018-2561-3.
PMID: 29562937DERIVED

MeSH Terms

Conditions

Intracranial Embolism

Interventions

Renal Replacement TherapyRenal Dialysis

Condition Hierarchy (Ancestors)

Intracranial Embolism and ThrombosisCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesThromboembolismEmbolism and Thrombosis

Intervention Hierarchy (Ancestors)

Study Officials

Gabor Erdoes, MD
University of Berne
PRINCIPAL INVESTIGATOR

Enrollment

66 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: NONE
Purpose: TREATMENT
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

November 20, 2015

First Posted

December 3, 2015

Study Start

January 2017

Date type not reported

This date has not been verified as actual or estimated.

Study Stopped

Cerebral Microembolism in the Critically Ill With Acute Kidney Injury

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Study Arms (2)

CRRT group

IRRT group

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Study Arms (2)

CRRT group

IRRT group

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Source record

Locations