Dietary Diversity is Associated With Maternal Anemia and Key Prenatal Outcomes in Ethiopia

NCT02620943 | Completed

• 1 other identifier: AAUT
• Study Type: observational
• Target: 374
• Locations: 1 country
• Sites: 1

Brief Summary

Background: Maternal and child under-nutrition is the underlying cause of death for millions across the globe. Anemia during pregnancy is among the leading nutritional disorders with serious short and long term consequences to both the mother and fetus. Objective: Examine the effect of dietary diversity on maternal anemia, nutritional status and key pregnancy outcomes of pregnancy. Methods: A prospective cohort study design, involving a total of 432 eligible pregnant women, in their second antenatal care visit was conducted between August 2014 to March, 2015. The individual dietary diversity Score (IDDS) was used as the exposure variable to select, enroll and follow the mothers. Epi-data, SPSS and STATA software are used to enter and analyze the data. Chi-square test, independent 't'-test, and GLM are used to calculate risk, association and differences between key variables at P \< 0.05

Conditions

Anemia; Low Birth Weight; Pre-Term Birth; Still Birth

Keywords

Anemia; Pregnancy Outcome; Pregnancy; Dietary Diversity; Birth Weight

Outcome Measures

Primary Outcomes (4)

• Change in Anemia during pregnancy

  Hemoglobin levels has been taken at each visit and were used for classification of outcomes

  Change from baseline (24- 28 weeks ) to 9 month of gestation).

• Low birth weight

  Birth weight was recorded immediately after delivery in gms at the center by attending

  Immediately at delivery

• Pre-term birth

  Gestational age was recorded in weeks at birth

  Immediately at delivery

• Still Birth

  Survival and living status of the baby was recorded at birth by midwives attending the labour

  Immediately at delivery

Study Arms (2)

Exposed Group

Pregnant mothers reporting inadequate (\<4) dietary diversity during pregnancy

Unexposed group

Pregnant mothers reporting adequate (\>=4) dietary diversity during pregnancy

Eligibility Criteria

• Age: 15 Years - 49 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Pregnant women in rural Ethiopia

You may qualify if:

• Pregnant women who are :
• Willing to stay in the study throughout the study
• Visit same health center for the antenatal and delivery care services
• pregnant mother has lived for at least six months in the study area

You may not qualify if:

• Pregnant women who have known medical, surgical or obstetric problems

Sponsors & Collaborators

• Dilla University: lead
• Addis Ababa University: collaborator
• African Population and Health Research Center: collaborator
• International Development Research Centre, Canada: collaborator

Study Sites (1)

Addis Ababa University, Center for FDSC and Nutrition

Addis Ababa, Select State, 1196, Ethiopia

Location

Related Publications (3)

• 1. Ruel MT. Is Dietary Diversity an Indicator of Food Security or Dietary Quality? A Review of Measurement Issues and Research Needs: Discussion Paper. Washington, DC 2006 USA; 2006. 2. UN Standing Committee on Nutrition. Fact sheets on Food and Nutrition Security Indicators/Measures: Dietary Diversity (DD). 2008. 3. Moges T, Birks KA, Samuel A, Kebede A, Zerfu D, Abera A, et al. Diet diversity is negatively associated with stunting among Ethiopian children 6-23 months of age. Addis Ababa, Ethiopia; 2013. 4. Arimond M, Ruel MT. Dietary Diversity, Dietary Quality, and Child Nutritional Status: Evidence from Eleven Demographic and Health Surveys. Am Soc Nutr Sci. 2004; 5. Acham H, Oldewage-theron WH, Egal AA. Dietary diversity , micronutrient intake and their variation among black women in informal settlements in South Africa : A cross-sectional study. 2012;4(February):24-39. 6. Papadaki A, Vardavas C, Hatzis C, Kafatos A. Calcium , nutrient and food intake of Greek Orthodox Christian monks during a fasting and non-fasting week. Public Health Nutr. 2007;11(10):1022-9. 7. Nevin S Scri nshat' and JPS. Synergism of nutrition , an overview13 and immunity. Am J Cli,, Nutr. 1997;66:464S - 77S. 8. Nutrition and Consumer Protection Division, FAO U. Guidelines for measuring household and individual dietary diversity. Rome, Italy; 2011. 9. Bilinsky AS and P. Household Dietary Diversity Score (HDDS) for Measurement of Household Food Access: Indicator Guide. 2006;Version 2. 10. Steyn NP, Nel JH, Nantel G, Kennedy G, Labadarios D. Food variety and dietary diversity scores in children : are they good indicators of dietary adequacy ? Public Health Nutr. 2006;9(5):644-50.

  RESULT

• Zerfu TA, Baye K, Faber M. Dietary diversity cutoff values predicting anemia varied between mid and term of pregnancy: a prospective cohort study. J Health Popul Nutr. 2019 Dec 13;38(1):44. doi: 10.1186/s41043-019-0196-y.

  PMID: 31836026 DERIVED

• Zerfu TA, Umeta M, Baye K. Dietary diversity during pregnancy is associated with reduced risk of maternal anemia, preterm delivery, and low birth weight in a prospective cohort study in rural Ethiopia. Am J Clin Nutr. 2016 Jun;103(6):1482-8. doi: 10.3945/ajcn.115.116798. Epub 2016 May 11.

  PMID: 27169832 DERIVED

MeSH Terms

Conditions

Anemia; Stillbirth; Birth Weight

Condition Hierarchy (Ancestors)

Hematologic Diseases; Hemic and Lymphatic Diseases; Fetal Death; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Death; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Body Weight; Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 25, 2015
• First Posted: December 3, 2015
• Study Start: August 1, 2014
• Primary Completion: March 1, 2015
• Study Completion: March 1, 2015
• Last Updated: December 3, 2015

Record last verified: 2015-11

Locations

ET (1)