Clinical Aspects of Patients With Benign Paroxysmal Positional Vertigo (BPPV) and Migraine

NCT02615314 | Completed

• 1 other identifier: AnadoluMC
• Study Type: observational
• Target: 232
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this study is to analyze the clinical aspects of patients with BPPV associated with migraine. It is our purpose to clarify weather migraine is a risk factor for BPPV if the clinical aspect and the therapeutic outcome is different.

Conditions

Migraine; Positional Vertigo

Keywords

migraine; benign paroxysmal positional vertigo

Outcome Measures

Primary Outcomes (1)

• Number of patients who had normal vestibular response to provocative tests 7 days after re-positioning maneuver

  Every patient with BPPV who had positional nystagmus during Dix-Hallpike and head-roll provocative maneuvers will be treated with Epley or barbeque particle re-positioning maneuvers. Balance (positional nystagmus) of patients 7 days after re-positioning maneuvers will be assessed.

  7 days

Study Arms (2)

BPPV without migraine

Two hundred and sixty-three patients with BPPV (2009-2014), confirmed by videonystagmography (VNG), were enrolled in the study. Patients' charts were reviewed. They were grouped as those with or without migraine. Distribution of gender, age, duration of symptoms and affected side were reviewed. Two hundred and thirty-one patients with no migraine were identified.

Procedure: Particle re-positioning maneuver

BPPV with migraine

Thirty-two patients (11.4%) with migraine were identified. Diagnosis and classification of migraine and its differentiation from other type of headaches was based on third edition of International classification of headache disorders (ICHD-III beta) by international headache society (IHS). All patients with migraine had migrainous headache with or without aura and they all were diagnosed in our institution and followed by our neurology staff.

Procedure: Particle re-positioning maneuver

Interventions

Particle re-positioning maneuver PROCEDURE

Patients with posterior canal BPPV (PC-BPPV) were treated with Epley maneuver. Patients with superior canal (SC-BPPV) were treated with Li or reverse Epley maneuver. Patients with lateral canal (LC) apogeotropic or geotropic nystagmus were treated with Barbeque, Semont's or Gufoni maneuvers. If geotropic or ageotropic type nystagmus is equal intensity on both sides. The involved side was determined according to the patient sense of disturbance or lying down positioning test. If the patient has involvement of both sides according to Dix-Hallpike maneuver. Therapeutic maneuver was applied to the more severe side. All patients were re-evaluated at maximum 7 days.

BPPV with migraine; BPPV without migraine

Eligibility Criteria

• Age: 10 Years - 84 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

BPPV patients only confirmed by VNG

You may qualify if:

• Patients who had history of head-induced positional and brief vertigo and who have been confirmed by VNG were included

You may not qualify if:

• Patients with balance problem other than BPPV,
• Patients receiving any medication prior to therapeutic maneuver were excluded

Sponsors & Collaborators

• Anadolu Medical Center: lead

Related Publications (4)

• Uneri A. Migraine and benign paroxysmal positional vertigo: an outcome study of 476 patients. Ear Nose Throat J. 2004 Dec;83(12):814-5.

  PMID: 15724736 RESULT

• Ishiyama A, Jacobson KM, Baloh RW. Migraine and benign positional vertigo. Ann Otol Rhinol Laryngol. 2000 Apr;109(4):377-80. doi: 10.1177/000348940010900407.

  PMID: 10778892 RESULT

• Yetiser S, Ince D. Demographic analysis of benign paroxysmal positional vertigo as a common public health problem. Ann Med Health Sci Res. 2015 Jan-Feb;5(1):50-3. doi: 10.4103/2141-9248.149788.

  PMID: 25745577 RESULT

• von Brevern M, Radtke A, Lezius F, Feldmann M, Ziese T, Lempert T, Neuhauser H. Epidemiology of benign paroxysmal positional vertigo: a population based study. J Neurol Neurosurg Psychiatry. 2007 Jul;78(7):710-5. doi: 10.1136/jnnp.2006.100420. Epub 2006 Nov 29.

  PMID: 17135456 RESULT

MeSH Terms

Conditions

Migraine Disorders; Vertigo; Benign Paroxysmal Positional Vertigo

Condition Hierarchy (Ancestors)

Headache Disorders, Primary; Headache Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vestibular Diseases; Labyrinth Diseases; Ear Diseases; Otorhinolaryngologic Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Meltem Hale Gokmen, MD

  Dept of Neurology, Anadolu Medical Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical Professor, Dept of ORL & HNS

Study Record Dates

• First Submitted: November 14, 2015
• First Posted: November 26, 2015
• Study Start: January 1, 2015
• Primary Completion: June 1, 2015
• Study Completion: July 1, 2015
• Last Updated: November 26, 2015

Record last verified: 2015-11