An Observational Pilot Study of Lumosity Computerized Cognitive Training in Subjects With Multiple Sclerosis

NCT02612935 | Completed

• 1 other identifier: LL009 - MS ACHIEVEMENT STUDY
• Study Type: observational
• Target: 88
• Locations: 0 countries
• Sites: N/A

Brief Summary

In collaboration with the Mercy MS Achievement Center, Lumos Labs is proposing an open-label, 12-month pilot study of computerized cognitive training as part of the cognitive wellness program in order to evaluate (1) the user experience of Lumosity in individuals with MS, and (2) the efficacy of Lumosity for improving cognitive outcomes in individuals with MS.

Conditions

Multiple Sclerosis (MS)

Outcome Measures

Primary Outcomes (1)

• Performance Characteristics and Usability measures of Lumosity, as measured by Self-Report Descriptive Questionnaires

  The primary objective is to determine performance characteristics and usability of Lumosity in individuals with MS as measured through qualitative questionnaires.

  1 year

Secondary Outcomes (6)

• Efficacy of Lumosity in individuals with MS, as measured with the BPT

  Change from baseline as measured at 3, 6, 9 and 12 months

• Efficacy of Lumosity in individuals with MS, as measured with the MSNQ

  1 Year

• Efficacy of Lumosity in individuals with MS, as measured with the MOCA

  1 Year

• Efficacy of Lumosity in individuals with MS, as measured with the MSIS-29.

  1 Year

• Efficacy of Lumosity in individuals with MS, as measured with the BDI.

  1 Year

Interventions

Lumosity DEVICE

Lumosity offers a suite of online games focused on stimulating cognitive domains of attention, memory, cognitive flexibility, problem solving, and speed of processing. The Lumosity program may be well suited for cognitive remediation in individuals with MS.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Approximately 50 current members of the Mercy MS Achievement Center will be provided with 12-month premium access Lumosity accounts. Study participants must be ≥18 years of age, and currently members of the Achievement Center participating in the cognitive wellness program.

You may qualify if:

• Participants must meet the following criteria:
• Signed informed consent
• years of age or older,
• English-speaking,
• Current participants in the MS Achievement Center Cognitive Wellness Program
• Sufficient physical capacity to use a computer keyboard and mouse
• Willing and able to use Lumosity at least 3 times per week

You may not qualify if:

• Participants who meet any of the following criteria will be excluded from participation:
• Under 18 years of age
• Are taking medication that may impede cognitive functioning
• Have other conditions or problems that may preclude regular computer usage

Sponsors & Collaborators

• Lumos Labs, Inc.: lead
• Dignity Health: collaborator

MeSH Terms

Conditions

Multiple Sclerosis

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases

Study Officials

• Brian Hutchinson

  MS Achievement Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 19, 2015
• First Posted: November 24, 2015
• Study Start: March 1, 2015
• Primary Completion: February 1, 2017
• Study Completion: February 1, 2017
• Last Updated: May 25, 2017

Record last verified: 2017-05