Meditative Movement for COPD Symptoms in Non-Smoking Flight Attendants

NCT02612389 | Completed

• 1 other identifier: 28572
• Study Type: interventional
• Target: 220
• Locations: 1 country
• Sites: 1

Brief Summary

This study will explore the a Qigong based exercise intervention, here referred to as Meditative Movement (MM), to ameliorate the symptoms associated with chronic obstructive pulmonary disease (COPD) and its co-morbidities. It tests the hypothesis that MM will have a beneficial effect on COPD in FA, particularly on functional ability, respiratory symptoms, affective state, inflammation, and autonomic imbalance. If the hypothesis is correct, MM could be rapidly and inexpensively taught to FA with COPD and other COPD patients to slow degeneration and improve quality of life.

Conditions

Pulmonary Disease; Autonomic Dysfunction; COPD

Keywords

COPD; Qigong; ANS; Meditative Movement; Flight Attendants; Secondhand Smoke; Nicotine; Blood Pressure; 6 minute walk test

Outcome Measures

Primary Outcomes (2)

• Change in 6 minute walk test

  Each participant walks as many ft as possible at a brisk pace. The amount of feet covered in 6 minutes is documented.

  Baseline, 4 months

• Change in C-reactive protein (CRP)

  At each assessment circulating CRP will be monitored via blood collected in form of fingerstick.

  Baseline, 4 months

Secondary Outcomes (10)

• Blood Pressure

  Baseline, 4 months

• Heart Rate

  Baseline, 4 months

• Oxygen Saturation

  Baseline, 4 months

• Spirometry: FEV1/FVC

  Baseline, 4 months

• Autonomic Function Self Report

  Baseline, 4 months

Study Arms (2)

MM Intervention taught via DVD

EXPERIMENTAL

Receive Meditative Movement training via DVD with pre and post interventional testing.

Other: Meditative Movement taught via DVD

MM Intervention Waitlist Control

NO INTERVENTION

Testing at same frequency as Meditative Movement interventional subjects.

Interventions

Meditative Movement taught via DVD OTHER

Gentle movement with attention to posture and breathing with emphasis on interoceptive awareness and self regulation.

Also known as: Qigong

MM Intervention taught via DVD

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Occupation as a flight attendant for at least 5 years
• No history of significant tobacco use
• Occupational controls

You may not qualify if:

• Inability to give consent
• History of tobacco habituation

Sponsors & Collaborators

• Dartmouth-Hitchcock Medical Center: lead
• Flight Attendant Medical Research Institute: collaborator
• ZRT Laboratory: collaborator
• Norris Cotton Cancer Center: collaborator

Study Sites (1)

Dartmouth Hitchcock Medical Center

Lebanon, New Hampshire, 03756, United States

Location

Related Publications (5)

• Zhang L, Xu Y. Impact of Radiation Therapy on Outcomes of Artificial Urinary Sphincter: A Systematic Review and Meta-Analysis. Front Surg. 2022 Feb 14;9:825239. doi: 10.3389/fsurg.2022.825239. eCollection 2022.

  PMID: 35237650 DERIVED

• Ye X, Gu Y, Bai Y, Xia S, Zhang Y, Lou Y, Zhu Y, Dai Y, Tsoi JK, Wang S. Does Low-Magnitude High-Frequency Vibration (LMHFV) Worth for Clinical Trial on Dental Implant? A Systematic Review and Meta-Analysis on Animal Studies. Front Bioeng Biotechnol. 2021 Apr 27;9:626892. doi: 10.3389/fbioe.2021.626892. eCollection 2021.

  PMID: 33987172 DERIVED

• Payne P, Fiering S, Zava D, Gould TJ, Brown A, Hage P, Gaudet C, Crane-Godreau M. Digital Delivery of Meditative Movement Training Improved Health of Cigarette-Smoke-Exposed Subjects. Front Public Health. 2018 Oct 19;6:282. doi: 10.3389/fpubh.2018.00282. eCollection 2018.

  PMID: 30406067 DERIVED

• Payne P, Fiering S, Leiter JC, Zava DT, Crane-Godreau MA. Effectiveness of a Novel Qigong Meditative Movement Practice for Impaired Health in Flight Attendants Exposed to Second-Hand Cigarette Smoke. Front Hum Neurosci. 2017 Feb 21;11:67. doi: 10.3389/fnhum.2017.00067. eCollection 2017.

  PMID: 28270757 DERIVED

• Payne P, Zava D, Fiering S, Crane-Godreau M. Meditative Movement as a Treatment for Pulmonary Dysfunction in Flight Attendants Exposed to Second-Hand Cigarette Smoke: Study Protocol for a Randomized Trial. Front Psychiatry. 2016 Mar 22;7:38. doi: 10.3389/fpsyt.2016.00038. eCollection 2016.

  PMID: 27047398 DERIVED

Related Links

• Payne P, et al. (2016) Meditative Movement as a Treatment for Pulmonary Dysfunction in Flight Attendants Exposed to Second-Hand Cigarette Smoke: Study Protocol for a Randomized Trial. Front. Psychiatry 7:38. doi: 10.3389/fps
• Payne P, et al. (2017) Effectiveness of a Novel Qigong Meditative Movement Practice for Impaired Health in Flight Attendants Exposed to Second-Hand Cigarette Smoke. Front. Hum. Neurosci. 11:67. doi: 10.3389/fnhu
• Payne P, Fiering S, Zava D, Gould TJ, Brown A, Hage P, Gaudet C and Crane-Godreau M (2018) Digital Delivery of Meditative Movement Training Improved Health of Cigarette-Smoke-Exposed Subjects. Front. Public Health 6:282. doi: 10.3389/fpubh.2018.00282
• Website for Body Mind Science. Investigators are no longer at Dartmouth. Future publication links will be at the BodyMind Science sites.

MeSH Terms

Conditions

Lung Diseases; Primary Dysautonomias; Pulmonary Disease, Chronic Obstructive

Interventions

Qigong

Condition Hierarchy (Ancestors)

Respiratory Tract Diseases; Autonomic Nervous System Diseases; Nervous System Diseases; Lung Diseases, Obstructive; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Breathing Exercises; Mind-Body Therapies; Complementary Therapies; Therapeutics; Exercise Movement Techniques; Physical Therapy Modalities

Study Officials

• Steven N Fiering, PhD

  Geisel School of Medicine, Faculty

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Scientist

Study Record Dates

• First Submitted: November 19, 2015
• First Posted: November 23, 2015
• Study Start: March 1, 2015
• Primary Completion: June 17, 2020
• Study Completion: July 17, 2020
• Last Updated: August 18, 2020

Record last verified: 2020-08

Locations

US (1)