The Different Analgesic Potency of Volatile Anesthetics at Equi-MAC
1 other identifier
interventional
77
1 country
1
Brief Summary
The aim of this clinical trial is to evaluate the difference of analgesic potency of sevoflurane and desflurane at equi-minimum alveolar concentration using a surgical pleth index.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for phase_3
Started Nov 2015
Shorter than P25 for phase_3
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 1, 2015
CompletedFirst Submitted
Initial submission to the registry
November 18, 2015
CompletedFirst Posted
Study publicly available on registry
November 20, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 28, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
July 28, 2016
CompletedNovember 8, 2017
November 1, 2017
9 months
November 18, 2015
November 6, 2017
Conditions
Outcome Measures
Primary Outcomes (1)
Analgesic potency of volatile anesthetics
The analgesic potency was evaluated by surgical pleth index value
the first 60 min of maintaining a steady state 1 MAC of volatile agents
Study Arms (2)
Sevoflurane
EXPERIMENTALAnesthesia was maintained with sevoflurane.
Desflurane
EXPERIMENTALAnesthesia was maintained with desflurane.
Interventions
Anesthesia was maintained with sevoflurane in patients undergoing arthroscopic shoulder surgery under general anesthesia and interscalene brachial plexus block.
Anesthesia was maintained with desflurane in patients undergoing arthroscopic shoulder surgery under general anesthesia and interscalene brachial plexus block.
Eligibility Criteria
You may qualify if:
- patients undergoing arthroscopic shoulder surgery
- patients with american society of anesthesiologist physical status I, II
- patients aged 19-65 years
- patients obtaining written informed consent
You may not qualify if:
- patients with a history of any psychiatric or neurological disease
- patients who had received any medication affecting the central nervous system
- patients who had received medication affecting the sympathetic or parasympathetic nervous systems
- patients who have not received interscalene approach brachial plexus block (refusal or failure)
- pregnant women
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Kangbuk Samsung Hospital
Seoul, 03181, South Korea
MeSH Terms
Conditions
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Kyoungho Ryu, M.D.
Kangbuk Samsung Hospital
Study Design
- Study Type
- interventional
- Phase
- phase 3
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Clinical assistant professor
Study Record Dates
First Submitted
November 18, 2015
First Posted
November 20, 2015
Study Start
November 1, 2015
Primary Completion
July 28, 2016
Study Completion
July 28, 2016
Last Updated
November 8, 2017
Record last verified: 2017-11