Memorisation of Phonologic Information Among Children With Oral Language Developement Disorder

NCT02609542 | Completed

• 1 other identifier: RC-P0029
• Study Type: observational
• Target: 173
• Locations: 1 country
• Sites: 1

Brief Summary

The disorder of oral language development is defined by the delay in language acquisition in children who possess efficient auditory acuity and normal non verbal intellect. The diversity of language developement disorders depends either in the expressive level or in the receptive level leading to divers syndromes and symptoms. These syndromes and symptoms are regrouped under the name of STOL (Specific Troubles of Oral Language). In the current project the visual exploitation and learning capability of children presenting a STOL condition will be compared to patients with a normal development. The investigator's hypothesis is as follows: STOL patients for whom the STOL disorder is reduced between 4 and 7 years of age will present a better performance at verbal memorisation, compared to patients with a persistent STOL condition after the age of 6.

Conditions

Language Development Disorders

Keywords

oral language; STOL; memory; eye tracking

Outcome Measures

Primary Outcomes (1)

• Changes from baseline in the score associated to speech-language outcome measured by a scale grouping results of different questionnaires

  We will determine if capacities of verbal memory of the children presenting STOL diagnosed at an early stage of their development (before 6 years) are predictive of the evolution of the disorder according to their cognitive profile and more specifically, their language profile as well as their tests performances. To measure the speech language outcome is necessary to take in consideration the score of more than one test performance.

  0,12, 24 months

Secondary Outcomes (6)

• Changes from baseline in the Raven's Progressive Matrices (RPM) test

  0,12, 24 months

• Changes from baseline in the Peabody Picture Vocabulary Test

  0,12, 24 months

• Changes from baseline in the number repetition test

  0,12, 24 months

• Changes from baseline in the sentences repetition test

  0,12, 24 months

• Changes from baseline in the non-words repetition test

  0,12, 24 months

Study Arms (2)

STOL group

STOL children will be recruited in the neuropediatric unit at the GHICL in Lille. Children will be followed and we will determine if capacities of verbal memory of the children presenting STOL diagnosed at an early stage of their development (before 6 years) are predictive of the evolution of the disorder according to their cognitive profile and more specifically, their language profile as well as their tests performances. The participants' eye movements ( visual world paradigm or eye tracking) will be recorded in order to determine the interplay between linguistic and visual information processing. Patients with a persistent STOL will be identified at the end of the follow up.

Other: Eye Tracking

Control group

Children with no language development disorder willing to participate in the study will be recruited at school. The participants' eye movements ( visual world paradigm or eye tracking) will be recorded in order to determine the interplay between linguistic and visual information processing.

Other: Eye Tracking

Interventions

Eye Tracking OTHER

Eye tracker will allows the recording of various information concerning eye fixation (number, duration, location) and saccadic eye movement (speed, range, number, duration) in order to determine the interplay between linguistic and visual information processing during tests performance

Also known as: visual world paradigm

Control group; STOL group

Eligibility Criteria

• Age: 45 Months - 95 Months
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

STOL children between 45 and 95 months of age at inclusion recruited at the neuropediatric consultation and control children of the same age recruited at schools

You may qualify if:

• A score \> or equal to 5 percentile on the non verbal intelligence test (PM47)
• Patient diagnosed with STOL by the neuropediatric medical team
• Coverage of the social insurance
• Consent form signed by the parents or the legal representative of the child
• Normal or corrected sight
• Normal hearing
• A score \> or equal to 5 percentile on the non verbal intelligence test (PM47)
• Child who did not receive any speech therapy
• Coverage of the social insurance
• Consent form signed by the parents or the legal representative of the child
• Normal or corrected sight
• Normal hearing

You may not qualify if:

• Mother language other than French
• Score \< to 5 percentile on the non verbal intelligence test (PM47)
• Child with pervasive developmental disorder
• Mother language other than French
• Score \< to 5 percentile on the non verbal intelligence test (PM47)
• Child who received speech therapy

Sponsors & Collaborators

• Lille Catholic University: lead

Study Sites (1)

Hôpital St Vincent-de-Paul (GHICL)

Lille, Hauts-de-France, 59000, France

Location

MeSH Terms

Conditions

Language Development Disorders

Condition Hierarchy (Ancestors)

Language Disorders; Communication Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Delphine Fleurion, Psychologist

  Groupement des Hôpitaux de l'Institut Catholique de Lille

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 4, 2015
• First Posted: November 20, 2015
• Study Start: March 1, 2014
• Primary Completion: May 1, 2023
• Study Completion: May 1, 2023
• Last Updated: December 4, 2025

Record last verified: 2025-11

Locations

FR (1)