NCT02603367

Brief Summary

This pilot clinical trial studies the COMFORT (C-Communication, O-Orientation and opportunity, M-Mindful presence, F-Family, O-Openings, R-Relating, and T-Team) caregiver intervention in improving communication and reducing distress in caregivers of patients with lung cancer. Caregivers of patients with cancer may experience stress and anxiety due to difficulty communicating with family, friends, and healthcare providers, or feeling unable to communicate openly. A communication intervention that improves the caregiver's ability to communicate with patients and healthcare providers may help reduce caregivers' psychological distress and improve the health outcomes of patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Nov 2015

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 10, 2015

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 11, 2015

Completed
13 days until next milestone

Study Start

First participant enrolled

November 24, 2015

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 10, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 10, 2017

Completed
Last Updated

August 15, 2017

Status Verified

August 1, 2017

Enrollment Period

1.7 years

First QC Date

November 10, 2015

Last Update Submit

August 11, 2017

Conditions

Outcome Measures

Primary Outcomes (5)

  • Attrition rate

    An electronic recruitment database will be created to document accrual, attrition, and retention rates.

    Up to 18 months

  • Change in caregiver psychological distress, measured using the Distress Thermometer

    Data will be summarized using descriptive statistics, including means for normally distributed continuous data, medians for non-normally distributed continuous data or proportions for categorical data. The established instruments will be scored according to standard instructions, and appropriate descriptive statistics will be computed. Outcomes will be compared pre- and post-intervention without full effectiveness analysis, as this is a pilot study.

    Baseline to 1 month post-intervention

  • Recruitment rate

    An electronic recruitment database will be created to document accrual, attrition, and retention rates.

    Up to 18 months

  • Retention rate

    An electronic recruitment database will be created to document accrual, attrition, and retention rates.

    Up to 18 months

  • Themes derived from qualitative content analysis

    Qualitative review of recruitment procedures and evaluation of research nurse feedback about intervention calls will be conducted. Content analysis will be conducted on the transcribed qualitative data. A qualitative summary of themes derived from study documents will be used. The intervention will be refined based on study results, and improvements made for it to be suited to a larger randomized, controlled trial.

    Up to 18 months

Secondary Outcomes (1)

  • Change in caregiver communication confidence, measured using the Caregiver Communication Survey

    Baseline to 1 month post-intervention

Study Arms (1)

Supportive care (COMFORT communication intervention)

EXPERIMENTAL

Participants receive the printed communication tool "A Communication Guide for Caregivers," a guide developed from the COMFORT communication curriculum, a national training program for palliative care communication. After a 1 week period to review the material, participants undergo communication coaching with a research nurse by phone over approximately 1 hour.

Other: Communication InterventionOther: Educational InterventionOther: Psychosocial Support for CaregiverOther: Questionnaire Administration

Interventions

Undergo communication coaching

Supportive care (COMFORT communication intervention)

Receive COMFORT communication curriculum

Also known as: Education for Intervention, Intervention, Educational
Supportive care (COMFORT communication intervention)

Undergo communication coaching

Supportive care (COMFORT communication intervention)

Complete questionnaires

Supportive care (COMFORT communication intervention)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Family caregivers will need to be the primary family caregiver as identified by the lung cancer patient (ten caregivers from each of the following cancer care continuum points will be recruited)
  • English-speaking
  • Cancer care continuum points are defined as follows:
  • Diagnosis: A lung cancer patient who has received diagnosis within the last 45 days but has not yet started treatment
  • Treatment: A lung cancer patients who has started initial treatment (chemotherapy, radiation, surgery) for diagnosis within the last 30 days, is actively receiving treatment, and has a prognosis of more than one year
  • Survivorship: A lung cancer patient who has completed treatment and who is clinically disease free at the time of caregiver enrollment to study
  • End of Life: A lung cancer patient who is estimated to have 6 months or less to live
  • All subjects must have the ability to understand and the willingness to participate in the informed consent process

You may not qualify if:

  • Research participants who do not speak or read English
  • Subjects, who in the opinion of the investigator, may not be able to comply with the safety monitoring requirements of the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

City of Hope Medical Center

Duarte, California, 91010, United States

Location

MeSH Terms

Interventions

Early Intervention, EducationalEducational StatusMethodsPsychiatric RehabilitationCaregivers

Intervention Hierarchy (Ancestors)

Child Health ServicesCommunity Health ServicesHealth ServicesHealth Care Facilities Workforce and ServicesPreventive Health ServicesSocioeconomic FactorsPopulation CharacteristicsInvestigative TechniquesRehabilitationTherapeuticsHealth Personnel

Study Officials

  • Elaine Wittenberg, PhD

    City of Hope Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 10, 2015

First Posted

November 11, 2015

Study Start

November 24, 2015

Primary Completion

August 10, 2017

Study Completion

August 10, 2017

Last Updated

August 15, 2017

Record last verified: 2017-08

Locations