Common Decision Making Deficits in Suicidal Behaviors and Eating Disorders

NCT02595164 | Unknown

• 1 other identifier: SHEBA-15-2191-EGA-CTIL
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

The role of impulsivity and its contribution to suicidal behavior seems intuitively clear. Empirical results have proved the existence of a relationship between the two yet many questions are left unanswered, especially what differentiates suicide ideators from attempters.. Obsessive thinking patterns are thought processes which share a repetitive behavior domain and are exerted by an inner voice. 3 types of obsessive thinking patterns are self destructive thoughts, ruminations and overvalued ideas. Impulsivity and obsessive thinking patterns are presumed to have a common mechanism of behaviors which are resulted from basal ganglia dysregulation and thus effect inhibition. Novel research in the field of decision making could help to learn more about behavioral patterns associated with self harm behavior and suicide. Eating Disorders involve suicidal and self harm behavior, which both feature impulsivity and obsessive thinking patterns. The investigators study proposes a 3-step theoretical model which asserts there is a connection between impulsivity, obsessive thinking and poor decision making, all effecting self harm behavior. Contemporary research has not been able to fully understand the nature of impulsivity and its effect on self harm behavior, including eating disorders symptoms, nor addressed the impact of obsessive thinking patterns on the latter. 100 female participants with Eating Disorders and suicidal behavior will be recruited for the proposed research. Subjects will be given self-report questionnaires and computerized behavioral tasks. A one way ANOVA of two eating disorder subgroups, impulsive and non impulsive, will be conducted, following a hierarchical multiple regression with self harm behavior being the dependent variable.

Conditions

Anorexia Nervosa; Bulimia Nervosa; Suicide; Parasuicide; Self-Injurious Behavior; Impulsive Behavior

Outcome Measures

Primary Outcomes (1)

• impulsive tendency

  computerized tasks

  throughout study completion, approximately 1 year

Secondary Outcomes (1)

• impulsivity self report

  throughout study completion, approximately 1 year

Study Arms (2)

Impulsive subjects

Subjects exhibiting impulsive symptoms Behavioral Task

Non-impulsive subjects

Subjects which do not exhibit impulsive symptoms Behavioral Task

Eligibility Criteria

• Age: 13 Years - 30 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

For our research we will recruit 100 participants from a sample of female patients, diagnosed with Eating Disorders and suicidal behavior, admitted to mental health departments in general and psychiatric hospitals. Diagnosis will be made by the hospital staff. After receiving approval from the medical staff participants will be interviewed, handed questionnaires and computerized tasks.

You may qualify if:

• Psychiatric Diagnosis of Bulimia Nervosa, Anorexia Nervosa

You may not qualify if:

• BMI \< 16

Sponsors & Collaborators

• Sheba Medical Center: lead
• Schneider Children's Hospital: collaborator

MeSH Terms

Conditions

Anorexia Nervosa; Bulimia Nervosa; Suicide; Suicide, Attempted; Self-Injurious Behavior; Impulsive Behavior

Condition Hierarchy (Ancestors)

Feeding and Eating Disorders; Mental Disorders; Behavioral Symptoms; Behavior

Study Officials

• Yari Gvion, DR

  Bar Ilan University

  STUDY DIRECTOR

Central Study Contacts

Eitan Gur, MD

CONTACT

+972-3-5305105; eitan.gur@sheba.health.gov.il

Eran Saghiv, MA

CONTACT

+972544860871

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 19, 2015
• First Posted: November 3, 2015
• Study Start: November 1, 2015
• Primary Completion: November 1, 2017
• Study Completion: November 1, 2019
• Last Updated: November 3, 2015

Record last verified: 2015-11