NCT02586532|Completed
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Sponsor study identifier
Secondary identifiers
observational
828
1 country
1
Study Start
October 19, 2015
Actual (reported)Primary Completion
June 5, 2020
Actual (reported)Study Completion
June 5, 2020
Actual (reported)Background: Epstein-Barr virus (EBV) can cause the cancer nasopharyngeal carcinoma (NPC). Early detection of NPC through screening can lead to better treatment outcomes than when it is found later. Currently, NPC is found through visual inspection with an endoscope. It is not clear how well this method works, especially for the identification of small, early cancers. Researchers want to see how well nasal endoscopy works to detect NPC compared to another method called magnetic resonance imaging (MRI). Objectives: To evaluate the sensitivity of endoscopy to detect prevalent NPC among people who screen positive for EBV antibodies. Eligibility: Participants of the NPC Early Detection Screening Program in China who: Have increased levels of EBV antibodies Are otherwise in good health and able to have an MRI procedure Design: Participants will be screened with a blood test. Participants will have a nasal endoscopy. Participants will have an MRI of the head and neck: Participants will have lesions identified by either the endoscopy or MRI biopsied and sent to a pathologist for review and diagnosis of NPC. Researchers will compare NPC detection rates by endoscopy and by MRI to see which method is better able to identify prevalent NPC. ...
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
June 5, 2020
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 19, 2015
Actual (reported)October 23, 2015
Actual (reported)October 26, 2015
Actual (reported)June 5, 2020
Actual (reported)June 5, 2020
Actual (reported)Concordance of Endoscopy and MRI screening for NPC
NPC
ongoing
Residents of towns participating in China Demonstration Project.
Residents of towns participating in China Demonstration Project.
Sun Yat-sen University Cancer Center (SYSUCC)
Guangzhou, China
Allan Hildesheim, Ph.D.
National Cancer Institute (NCI)
828 participants (actual enrollment reported by the registry).
First Submitted
October 23, 2015
First Posted
October 26, 2015
Study Start
October 19, 2015
Actual (reported)Maintenance Immunotherapy With Deferred Salvage Radiotherapy After Response to Chemoimmunotherapy in Recurrent Nasopharyngeal Carcinoma
International Collaborative Study on AJCC/UICC TNM-10 for Nasopharyngeal Cancer
Contact the study team to confirm eligibility.
Primary Completion
June 5, 2020
Actual (reported)Study Completion
June 5, 2020
Actual (reported)Last Updated
December 11, 2020
Record last verified: 2020-12
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Source: ClinicalTrials.gov.
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