Postural Control During Walking and Standing Among Children With Autism Spectrum Disorder

NCT02584972 | Completed DMC

• 1 other identifier: Sor 274-13 CTIL
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 2

Brief Summary

Lately, many researchers have found that Children with autism spectrum disorder (ASD) are most likely to have gross motor deficiencies such as lack of coordination in gait and balance. Much has been researched on etiology and motor learning, but only very few researches have examined and analyzed quantitatively gait and balance in ASD. The aim of this research is to analyze quantitatively balance, gait and balance during perturbation in children with ASD and to compare with typically developed children (TD). A group of 20 children diagnosed with ASD and a control group of 20 TD children will be recruited and tested in the laboratory with well-established measures of gait and balance function. They will be instructed to stand as still as possible on a force plate with different task conditions : (1) standing with the eyes open (EO) - standing upright viewing an "X" displayed on a screen 3 meters in front of them; (2) eyes closed (EC) - same as (1) with the eyes closed and covered by blindfolds (i.e. no visual information). (3) Same as 1 standing on foam (i.e., conflicting proprioceptive information). Gait will be measured using the narrow base walk test, modified for clinical use. Participants will be asked to walk within a narrow path 6 meters long . The statistical analysis will include Independent T-tests to compare the ASD and controls with respect to different characteristics. General Linear Model (GLM) will be used by applying a separate model where the dependent variables will be the average values of the postural stability or gait stability parameters (continuous) and the independent variables were categorical by the group and task condition.

Conditions

Autism Spectrum Disorder

Keywords

Postural control; Gait; Children; Autism Spectrum Disorder

Outcome Measures

Primary Outcomes (1)

• postural stability measures

  baseline

Secondary Outcomes (1)

• 6 meter Narrow Path Walking Test

  baseline

Study Arms (2)

children with Autism Spectrum Disorder

no intervention required

Other: no intervention required

heathy children

no intervention required

Other: no intervention required

Interventions

no intervention required OTHER

no intervention required

children with Autism Spectrum Disorder; heathy children

Eligibility Criteria

• Age: 6 Years - 12 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

children with autism spectrum disorder

You may qualify if:

• children with autism spectrum disorder
• years old
• able to walk independently

You may not qualify if:

• ASD children who were diagnosed with neurological, orthopedic, or psychiatric diagnoses according to DSM-IV criteria that can affect motor control and postural stability;
• cerebral palsy; - neuropathic diseases;
• limb fracture;
• head trauma during the previous year;
• who had an IQ score below the normal range (\<70), as assessed by the Wechsler Intelligence Scale for Children - Revised (Wisc-R) administered by a child psychologist.

Sponsors & Collaborators

• Soroka University Medical Center: lead

Study Sites (2)

Ben-guion University of the Negev,

Beersheba, 84105, Israel

Location

Soroka University Medical Center

Beersheba, Israel

Location

MeSH Terms

Conditions

Autism Spectrum Disorder

Condition Hierarchy (Ancestors)

Child Development Disorders, Pervasive; Neurodevelopmental Disorders; Mental Disorders

Study Officials

• Itshak Melzer, Phd

  Ben-Gurion University of the Negev

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate professor

Study Record Dates

• First Submitted: October 18, 2015
• First Posted: October 23, 2015
• Study Start: November 1, 2015
• Primary Completion: October 1, 2017
• Study Completion: October 1, 2017
• Last Updated: July 30, 2021

Record last verified: 2021-07

Locations

IL (2)