NCT02580175

Brief Summary

Abortion is considered the most common cause of fetal demise all over the world. The majority of cases occur in the first trimester. The termination of abortion may be by medical or surgical methods, however; the surgical methods represent the greater part of termination. Therefore, the safety of this procedure is a worldwide public health concern. Many clinical studies have reported the safety of surgical evacuation in the first trimester. The suction-aspiration or vacuum aspiration is the most common surgical method of induced abortion. This consists of removing the fetus, embryo, placenta, and membranes by suction using a manual syringe or electric pump. However; these techniques always need cervical dilation before aspiration. The menstrual extraction does not require cervical dilation and can be used in very early pregnancy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2014

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2014

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2015

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2015

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

October 17, 2015

Completed
3 days until next milestone

First Posted

Study publicly available on registry

October 20, 2015

Completed
Last Updated

July 31, 2024

Status Verified

July 1, 2024

Enrollment Period

11 months

First QC Date

October 17, 2015

Last Update Submit

July 30, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Measurement of endometrial thickness by ultrasound (mm)

    1 month

Secondary Outcomes (3)

  • Measurement of blood loss (mL)

    1 month

  • measurement of operative time (minutes)

    1 month

  • measurement of Hemoglobin level(g/ml)

    1 month

Study Arms (2)

Blinded evacuation

ACTIVE COMPARATOR

Ring evacuation was performed in the conventional way without use of ultrasound followed by sharp gentle curettage until complete evacuation

Procedure: Blinded evacuation

Evacuation under ultrasound guidance

ACTIVE COMPARATOR

Ring evacuation was performed under ultrasound guidance followed by sharp gentle curettage until complete evacuation. The surgery was considered complete when the endometrial cavity appeared as a regular echogenic line.

Procedure: Evacuation under ultrasound guidance

Interventions

Ring evacuation was performed in the conventional way without use of ultrasound followed by sharp gentle curettage until complete evacuation.

Blinded evacuation

Ring evacuation was performed under ultrasound guidance followed by sharp gentle curettage until complete evacuation. The surgery was considered complete when the endometrial cavity appeared as a regular echogenic line.

Evacuation under ultrasound guidance

Eligibility Criteria

Age20 Years - 40 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • women with non-viable first trimester intrauterine pregnancy
  • no contraindication to surgical evacuation under general anesthesia

You may not qualify if:

  • gestational age more than 13 weeks
  • hemodynamically unstable
  • suspicion of an ectopic pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Women Health Hospital - Assiut university

Asyut, 71111, Egypt

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr

Study Record Dates

First Submitted

October 17, 2015

First Posted

October 20, 2015

Study Start

May 1, 2014

Primary Completion

April 1, 2015

Study Completion

May 1, 2015

Last Updated

July 31, 2024

Record last verified: 2024-07

Locations