Multisensorial Information's Treatment in Autism Spectrum Disorder

NCT02579109 | Completed

• 1 other identifier: 13AOI09
• Study Type: interventional
• Target: 38
• Locations: 0 countries
• Sites: N/A

Brief Summary

Introduction: Autism spectrum disorder is characterized by deficits in three functional domains: language and communication, social reciprocity, and the presence of restricted interests/repetitive behaviors. There's also deficits in social cognition. When having a face-to-face conversation, a listener not only hears what a speaker is saying, but also sees the articulatory gestures that accompany those sounds. Speech signals needs then a multisensory processing. Impairments in multisensory perceptual binding may be particularly relevant in ASD, given that hallmark features of the disorder include difficulties in speech, communication, and social interactions. Objectives: The investigator suggest that atypical multisensory processing in ASD may have an impact on speech perception and social processing. Aims: Methods: This pilot study measures free recall scores in 3 lists of words presentation after 30 minutes. In the first condition (CI) words are only listening. In the second condition (CII) words are associated with a picture of a mans face. In the third condition (CIII) words are associated with a video of a man speaking. Three lists are homogeneous form words characteristics (lexical frequency, emotional valence norm, imageability). Participants were 7- to 13-year-olds typically developing children (TD) (N = 19) and ASD children (N = 19). The investigator would create some new tools for exploring the treatment of a social information. These tools should be the closest of a ecological social interaction.

Conditions

Autism

Outcome Measures

Primary Outcomes (1)

• rate of reminder after 30 minutes between the group autistic and the group witness( %)

  Comparison between the group autistic and the group witness of the difference enter the rate of reminder(abseiling) in 30 minutes of the words proposed in video and audio sequences.

  30 minutes

Secondary Outcomes (1)

• Difference of the scores of reminders words (%)

  30 minutes

Study Arms (2)

autistic patient

OTHER

patient with autistic trouble

Other: memory test

healthy volunteers

OTHER

healthy volunteers

Other: memory test

Interventions

memory test OTHER

autistic patient; healthy volunteers

Eligibility Criteria

• Age: 7 Years - 13 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• Boy or girl,
• years,
• Presenting a diagnosis DSM IV of disorder(confusion) of the autistic spectre: detected by the scale(ladder) ADI ( Autism Diagnostic Interview) or by TEENAGERS (Autism Diagnostic Observation Schedule): typical autistic. These patients do not answer the diagnosis of psychosis according to Kiddie-SADS,
• French-speaking children,
• Signature of the informed consent by the parents(relatives) and the child,
• Membership to the Social Security.

You may not qualify if:

• Genetic, neurological or neurosensory pathologies,
• Diagnosis of intrusive disorder(confusion) of the not specified development: TED our,
• The patients will not be included who would participate in a program or a study of reeducation in the social fitnesses.

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Nice: lead

MeSH Terms

Conditions

Autistic Disorder

Condition Hierarchy (Ancestors)

Autism Spectrum Disorder; Child Development Disorders, Pervasive; Neurodevelopmental Disorders; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 29, 2015
• First Posted: October 19, 2015
• Study Start: February 1, 2014
• Primary Completion: February 1, 2014
• Study Completion: August 1, 2014
• Last Updated: October 19, 2015

Record last verified: 2015-10