NCT02575677

Brief Summary

Oxycodone is used to treat early labour pain instead of meperidine. However, the efficacy and effects of oxycodone to the newborn has not been studied. In the present study, patient who has received oxycodone is asked about pain relief and after labour single venous blood sample from the parturient and umbilical cord are taken for the analysis of oxycodone.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
90

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Oct 2012

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2012

Completed
3 years until next milestone

First Submitted

Initial submission to the registry

October 8, 2015

Completed
7 days until next milestone

First Posted

Study publicly available on registry

October 15, 2015

Completed
8.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2023

Completed
Last Updated

March 16, 2023

Status Verified

March 1, 2023

Enrollment Period

11.2 years

First QC Date

October 8, 2015

Last Update Submit

March 14, 2023

Conditions

Keywords

labor painoxycodone

Outcome Measures

Primary Outcomes (1)

  • Pain measured with numerical rating scale

    Pain measured with numerical rating scale 0-10 (0=no pain, 10 = worst pain)

    from the time of oxycodone administration up to the birth of newborn, maximum of 48 hours

Study Arms (1)

Parturients with oxycodone

Parturients who were given oxycodone

Other: oxycodone

Interventions

oxycodone 0,1/kg up to 10 mg sc.

Also known as: Ocycodone administration
Parturients with oxycodone

Eligibility Criteria

Age18 Years - 65 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Parturients who are in early labor and need some pain medication.

You may qualify if:

  • Oxycodone for pain relief
  • age 18 years or more
  • given informed consent

You may not qualify if:

  • no oxycodone
  • age less than 18 years
  • no informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kuopio University Hospital

Kuopio, Northern Savonia, 70029, Finland

RECRUITING

Biospecimen

Retention: SAMPLES WITHOUT DNA

venous blood for the analysis of oxycodone

MeSH Terms

Conditions

Labor Pain

Interventions

Oxycodone

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

CodeineMorphine DerivativesMorphinansOpiate AlkaloidsAlkaloidsHeterocyclic CompoundsHeterocyclic Compounds, Bridged-RingHeterocyclic Compounds, 4 or More RingsHeterocyclic Compounds, Fused-RingPhenanthrenesPolycyclic Aromatic HydrocarbonsPolycyclic Compounds

Study Officials

  • Merja Kokki, MD, PhD

    Kuopio University Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Merja Kokki, PhD

CONTACT

Hannu Kokki, professor

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, PhD

Study Record Dates

First Submitted

October 8, 2015

First Posted

October 15, 2015

Study Start

October 1, 2012

Primary Completion

December 1, 2023

Study Completion

December 1, 2023

Last Updated

March 16, 2023

Record last verified: 2023-03

Data Sharing

IPD Sharing
Will not share

Locations