Predictors of Mortality in Patients With Advanced Lung Disease in Home Oxygen Therapy

NCT02571582 | Completed

• 1 other identifier: Study of Advanced Lung Disease
• Study Type: observational
• Target: 553
• Locations: 0 countries
• Sites: N/A

Brief Summary

Advanced Pulmonary Disease (PAD) is a condition that affects countless individuals around the world. Patients are often functionally very limited, with premature death, which is due to the disease itself or its complications. Currently, there are numerous monitoring centers of these patients to increase survival, reduce costs and humanize care in these patients.

Conditions

Chronic Obstructive Pulmonary Disease and Allied Conditions

Keywords

Predictors of mortality

Outcome Measures

Primary Outcomes (1)

• Determine the predictors of mortality in patients with DPA in use of ODP

  Evaluate the results of evaluations carried out in patients who died and had advanced lung disease diagnosis in use of home oxygen, compared to patients who did not die and the normal population

  6 years

Secondary Outcomes (2)

• Assess adherence to the use of home oxygen and its relation to the survival of these patients;

  6 years

• To evaluate the influence of quality of life in patient survival;

  6 years

Other Outcomes (1)

• Identify the causes of mortality of these patients.

  6 years

Study Arms (2)

Patients died

All patients underwent extensive evaluation: \- Body composition, Diabetes; dyslipidemia, hemoconcentration, hypertension, exercise capacity: 6-Minute Walk test procedure, renal function, inflammatory markers, cause and place of death, time tracking concentrator, quality of life and pulmonary Function.

living patients

All patients underwent extensive evaluation: \- Body composition, Diabetes; dyslipidemia, hemoconcentration, hypertension, exercise capacity: 6-Minute Walk test procedure, renal function, inflammatory markers, cause and place of death, time tracking concentrator, quality of life and pulmonary Function.

Eligibility Criteria

• Age: 15 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All Patients with established diagnosis of advanced lung disease that makes / made long home Oxygen use which were accompanied or followed at Oxygen Therapy Clinic of the Federal University of Uberlândia (UFU) by the Home Care Program (PAD), from 2009 to 2015. The sampling is for convenience.

You may qualify if:

• Advanced Pulmonary disease using home oxygen therapy;
• Have a diagnosis of chronic hypoxemia proven by blood gas analysis on room air PaO 2 ≤ 55 mm Hg or SaO2 ≤ 88; or PaO2 between 55 and 60 mmHg or SaO2 between 89 and 90%, with evidence of pulmonary hypertension, or polycythemia (hematocrit\> 55%) as GOLD - Global Obstructive Lung Disease, 2015;

You may not qualify if:

• No records found Patients who failed to perform the periodic reviews established by the team responsible

Sponsors & Collaborators

• Federal University of Uberlandia: lead

Related Publications (7)

• Holmes DR Jr, Dehmer GJ, Kaul S, Leifer D, O'Gara PT, Stein CM. ACCF/AHA clopidogrel clinical alert: approaches to the FDA "boxed warning": a report of the American College of Cardiology Foundation Task Force on clinical expert consensus documents and the American Heart Association endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. J Am Coll Cardiol. 2010 Jul 20;56(4):321-41. doi: 10.1016/j.jacc.2010.05.013. No abstract available.

  PMID: 20633831 RESULT

• ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories. ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002 Jul 1;166(1):111-7. doi: 10.1164/ajrccm.166.1.at1102. No abstract available.

  PMID: 12091180 RESULT

• Tomioka K, Iwamoto J, Saeki K, Okamoto N. Reliability and validity of the International Physical Activity Questionnaire (IPAQ) in elderly adults: the Fujiwara-kyo Study. J Epidemiol. 2011;21(6):459-65. doi: 10.2188/jea.je20110003. Epub 2011 Sep 24.

  PMID: 21946625 RESULT

• Shah T, Jagpal S, Beckford R. Long-acting bronchodilators in patients with chronic obstructive pulmonary disease: still more to know. Ann Am Thorac Soc. 2014 Nov;11(9):1504. doi: 10.1513/AnnalsATS.201409-439LE. No abstract available.

  PMID: 25423005 RESULT

• Kim AL, Kwon JC, Park I, Kim JN, Kim JM, Jeong BN, Yu SK, Lee BK, Kim YJ. Reference equations for the six-minute walk distance in healthy korean adults, aged 22-59 years. Tuberc Respir Dis (Seoul). 2014 Jun;76(6):269-75. doi: 10.4046/trd.2014.76.6.269. Epub 2014 Jun 28.

  PMID: 25024720 RESULT

• Long term domiciliary oxygen therapy in chronic hypoxic cor pulmonale complicating chronic bronchitis and emphysema. Report of the Medical Research Council Working Party. Lancet. 1981 Mar 28;1(8222):681-6.

  PMID: 6110912 RESULT

• Velloso M, Jardim JR. Functionality of patients with chronic obstructive pulmonary disease: energy conservation techniques. J Bras Pneumol. 2006 Nov-Dec;32(6):580-6. doi: 10.1590/s1806-37132006000600017. English, Portuguese.

  PMID: 17435910 RESULT

Related Links

• The Global Initiative for Chronic Obstructive Lung Disease (GOLD) works with health care professionals and public health officials to raise awareness of Chronic Obstructive Pulmonary Disease (COPD) and to improve prevention and treatment of this lung di

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Vinícius Oliveira, Pafume

  Federal Principal Investigator

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physiotherapist

Study Record Dates

• First Submitted: October 6, 2015
• First Posted: October 8, 2015
• Study Start: January 1, 2009
• Primary Completion: September 1, 2015
• Study Completion: October 1, 2015
• Last Updated: October 8, 2015

Record last verified: 2015-10