NCT02569424|Completed
Effect of PEEP and Trendelenburg on Ultrasound Size of Internal Jugular and Subclavian Veins
PEEPUS
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PEEPUS
Sponsor study identifier
Secondary identifiers
REGISTRY · 2015-A00606-43
interventional
42
1 country
1
Study Start
September 2015
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2016
Actual (reported)Study Completion
December 2016
Actual (reported)There is no recommendation for the management of the positive end-expiratory pressure (PEEP) during setting of a central venous catheter (CVC) in a ventilated patient. Several non-randomized studies have investigated the cross-sectional area (AST) ultrasound minor axis for different pressure levels by evaluating a single vessel every time or by not displaying the right or left side in the evaluation. Another study showed that there could be unpredictable size differences between the 2 subclavian veins. In ventilated patient, the PEEP, which is intrathoracic, will result in a decrease of venous return and thus possibly a superior vena cava dilation, located outside the pleura, depending on their capacitance. Different pressure levels showed an increase of AST with the increase of intra-thoracic pressure on certain veins, in a heterogeneous and not randomized manner. The primary purpose of the study is to measure the effect of PEEP (0, 5, 10 or 15 cm H2O) and the patient's position (supine or Trendelenburg strict -15-20 °) on the cross-sectional area of the jugular and subclavian veins.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2016
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 2015
Date type not reportedThis date has not been verified as actual or estimated.
September 24, 2015
Actual (reported)October 6, 2015
Actual (reported)December 2016
Actual (reported)December 2016
Actual (reported)The cross-sectional area of the jugular veins ( in cm2)
The cross-sectional area of the jugular veins ( in cm2) at the end of the intervention
at baseline
The cross-sectional area of the subclavian veins ( in cm2)
at baseline
The antero-posterior diameter of the jugular veins (in mm)
at baseline
The antero-posterior diameter of the subclavian veins (in mm)
at baseline
The distance between posterior and pleural lining of the jugular veins (in mm)
at baseline
The distance between posterior and pleural lining of the subclavian veins (in mm)
at baseline
Patient's position (Supine or Trendelenburg strict -20°)
Supine or Trendelenburg strict -20°)
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
CHU Clermont-Ferrand
Clermont-Ferrand, 63003, France
Sébastien PERBET
University Hospital, Clermont-Ferrand
42 participants (actual enrollment reported by the registry).
First Submitted
September 24, 2015
First Posted
October 6, 2015
Study Start
September 2015
Date type not reportedThis date has not been verified as actual or estimated.
The Rapid Shallow Breathing Index (RSBI) is a Widely Used Predictor for Weaning Patients From Mechanical Ventilation This Study Aims to Determine the Predictive Value of RSBI Measurements for Extubation Success in Mechanically Ventilated ICU Patients
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Primary Completion
December 2016
Actual (reported)Study Completion
December 2016
Actual (reported)Last Updated
December 5, 2016
Record last verified: 2016-12
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Source: ClinicalTrials.gov.
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