NCT02568384

Brief Summary

The purpose of this study is to assess the usability of the Onyx system in the hands of subjects with Insulin Dependent Diabetes Mellitus (IDDM) or insulin-using subjects with Non-IDDM.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
45

participants targeted

Target at P25-P50 for not_applicable diabetes-mellitus

Timeline
Completed

Started Oct 2015

Shorter than P25 for not_applicable diabetes-mellitus

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2015

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

October 2, 2015

Completed
3 days until next milestone

First Posted

Study publicly available on registry

October 5, 2015

Completed
27 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2015

Completed
1.8 years until next milestone

Results Posted

Study results publicly available

August 25, 2017

Completed
Last Updated

August 25, 2017

Status Verified

August 1, 2017

Enrollment Period

1 month

First QC Date

October 2, 2015

Results QC Date

December 30, 2016

Last Update Submit

August 24, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Percent of Responses From Persons Who Performed Each "Software Operations" Task and Rated Each Statement as Strongly Agree, Agree, or Neither Agree Nor Disagree.

    For "software operations" tasks, subjects rated statements about software operations tasks as 1Strongly Agree, 2Agree, 3Neither Agree nor Disagree, 4Disagree, 5Strongly Disagree, or 6No opinion. Software operations tasks included: * Obtain a synced blood glucose reading * Initiation and use of insulin bolus calculator * Access and interpret glucose displays such as expanded graph (modal day) and sequential views.

    3 weeks

Secondary Outcomes (2)

  • Percent of Responses From Persons With Diabetes That Rated Ease of Use For Onyx Glucose Meter and App System as Either Very Simple or Simple or Neither Simple Nor Difficult

    3 weeks

  • Percent of Responses From Persons With Diabetes That Either 'Strongly Agree' or 'Agree' or Are 'Neither Agree Nor Disagree' With Questionnaire Statements Regarding Clarity and Utility of User Instructions For Onyx Glucose Meter and App System

    3 weeks

Other Outcomes (4)

  • HbA1c% From Study Start to End of Study

    3 weeks

  • Average Change in Subject Fructosamine From Study Start to End of Study

    3 weeks

  • Average Change in Subject Body Weight From Study Start to End of Study

    3 weeks

  • +1 more other outcomes

Study Arms (1)

Users of Onyx BG Meter / App System

EXPERIMENTAL

Subjects with diabetes used the Onyx Blood Glucose (BG) Meter / App System at home. The enrollment goal for the intended use population: 1. 40 to 70% of subjects will have type 1 diabetes 2. Not more than 30% of subjects will use an insulin pump

Device: Onyx BG Meter / App System

Interventions

Subjects with diabetes used the Onyx BG Meter / App System at home and assessed software operations, ease of use of the system, and clarity and utility of user instructions.

Users of Onyx BG Meter / App System

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Be aged 18-75 years, male or female
  • Read and understand English
  • Have diagnosis of type 1 or insulin-using type 2 diabetes for at least 6 months
  • Be taking multiple daily injections (MDI) of at least two pre-meal bolus injections daily or using an insulin pump
  • Performing self-monitoring of blood glucose at home at least twice daily
  • Have an iOS mobile device or Android mobile device with blue tooth capability
  • iOS device: iPod or iPhone 5 or later version with iOS 8.0 software or higher (no tablets)
  • Android: smart phone, 4.4 version and higher (no tablets)
  • Be willing to utilize the ONYX App on personal mobile device which communicates to meter to manage diabetes (including use of the bolus calculator)
  • Be ambulatory and have transportation to the study site

You may not qualify if:

  • Hemophilia or any other bleeding disorder
  • Pregnancy
  • Physical, visual or neurological impairments that would make the person unable to perform testing with the BGM
  • Working for a competitive medical device company, or having an immediate family member or someone who is not a family member but is living within the household of someone who works for such a company.
  • Proliferative retinopathy or history of retinal laser surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

AMCR Institute

Escondido, California, 92025, United States

Location

MeSH Terms

Conditions

Diabetes Mellitus

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Results Point of Contact

Title
Jane Wallace, Deputy Director for Global Clinical Affairs
Organization
Ascensia Diabetes Care

Study Officials

  • Timothy Bailey, MD

    AMCR Institute Inc.

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
GT60
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 2, 2015

First Posted

October 5, 2015

Study Start

October 1, 2015

Primary Completion

November 1, 2015

Study Completion

November 1, 2015

Last Updated

August 25, 2017

Results First Posted

August 25, 2017

Record last verified: 2017-08

Locations