NCT02563626

Brief Summary

International registry gathering patients with angiographically confirmed coronary aneurysm.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,565

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2015

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2015

Completed
25 days until next milestone

First Submitted

Initial submission to the registry

September 26, 2015

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 30, 2015

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2016

Completed
Last Updated

January 25, 2022

Status Verified

January 1, 2022

Enrollment Period

1.3 years

First QC Date

September 26, 2015

Last Update Submit

January 9, 2022

Conditions

Coronary Artery Aneurysm

Keywords

coronary artery aneurysmprognosisoutcomesmanagementincidenceheart failureacute coronary syndromedeath

Outcome Measures

Primary Outcomes (2)

  • Any cause death

    dicotomic variable (yes/no)

    12 months

  • Cardiology readmission

    dicotomic variable (yes/no)

    12 months

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients with a coronary aneurysm diagnosis.

You may qualify if:

  • Coronary aneurysm: focal coronary dilatation which exceeds the diameter of normal adjacent segments or the diameter of the patient's largest coronary vessel by 1.5 times.

You may not qualify if:

  • Patient ´s refusal to participate.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital Clínico San Carlos

Madrid, 28040, Spain

Location

Related Publications (9)

  • SCOTT DH. Aneurysm of the coronary arteries. Am Heart J. 1948 Sep;36(3):403-21. doi: 10.1016/0002-8703(48)90337-8. No abstract available.

    PMID: 18880707BACKGROUND

  • Swaye PS, Fisher LD, Litwin P, Vignola PA, Judkins MP, Kemp HG, Mudd JG, Gosselin AJ. Aneurysmal coronary artery disease. Circulation. 1983 Jan;67(1):134-8. doi: 10.1161/01.cir.67.1.134.

    PMID: 6847792BACKGROUND

  • Syed M, Lesch M. Coronary artery aneurysm: a review. Prog Cardiovasc Dis. 1997 Jul-Aug;40(1):77-84. doi: 10.1016/s0033-0620(97)80024-2.

    PMID: 9247557BACKGROUND

  • Dutary J, Zakhem B, DE Lucas CB, Paulo M, Gonzalo N, Alfonso F. Treatment of a giant coronary artery aneurysm: intravascular ultrasound and optical coherence tomography findings. J Interv Cardiol. 2012 Feb;25(1):82-5. doi: 10.1111/j.1540-8183.2011.00659.x. Epub 2011 May 22.

    PMID: 21599751BACKGROUND

  • Maehara A, Mintz GS, Ahmed JM, Fuchs S, Castagna MT, Pichard AD, Satler LF, Waksman R, Suddath WO, Kent KM, Weissman NJ. An intravascular ultrasound classification of angiographic coronary artery aneurysms. Am J Cardiol. 2001 Aug 15;88(4):365-70. doi: 10.1016/s0002-9149(01)01680-0.

    PMID: 11545755BACKGROUND

  • Nunez-Gil IJ, Nombela-Franco L, Bagur R, Bollati M, Cerrato E, Alfonso E, Liebetrau C, De la Torre Hernandez JM, Camacho B, Mila R, Amat-Santos IJ, Alfonso F, Rodriguez-Olivares R, Camacho Freire SJ, Lozano I, Jimenez Diaz VA, Piraino D, Latini RA, Feltes G, Linares JA, Mancone M, Ielasi A, Sanchez-Grande Flecha A, Fernandez Cisnal A, Ugo F, Jimenez Mazuecos JM, Omede P, Pavani M, Villablanca PA, Louka BF, Fernandez-Ortiz A; CAAR Investigators. Rationale and design of a multicenter, international and collaborative Coronary Artery Aneurysm Registry (CAAR). Clin Cardiol. 2017 Aug;40(8):580-585. doi: 10.1002/clc.22705. Epub 2017 Mar 24.

    PMID: 28337781RESULT

  • Nunez-Gil IJ, Cerrato E, Bollati M, Nombela-Franco L, Terol B, Alfonso-Rodriguez E, Camacho Freire SJ, Villablanca PA, Amat Santos IJ, de la Torre Hernandez JM, Pascual I, Liebetrau C, Camacho B, Pavani M, Albistur J, Latini RA, Varbella F, Jimenez-Diaz VA, Piraino D, Mancone M, Alfonso F, Linares JA, Rodriguez-Olivares R, Jimenez Mazuecos JM, Palazuelos Molinero J, Sanchez-Grande Flecha A, Gomez-Hospital JA, Ielasi A, Lozano I, Omede P, Bagur R, Ugo F, Medda M, Louka BF, Kala P, Escaned J, Bautista D, Feltes G, Salinas P, Alkhouli M, Macaya C, Fernandez-Ortiz A; CAAR investigators. Coronary artery aneurysms, insights from the international coronary artery aneurysm registry (CAAR). Int J Cardiol. 2020 Jan 15;299:49-55. doi: 10.1016/j.ijcard.2019.05.067. Epub 2019 Jul 19.

    PMID: 31378382RESULT

  • D'Ascenzo F, Saglietto A, Ramakrishna H, Andreis A, Jimenez-Mazuecos JM, Nombela-Franco L, Cerrato E, Liebetrau C, Alfonso-Rodriguez E, Bagur R, Alkhouli M, De Ferrari GM, Nunez-Gil IJ; CAAR Investigators. Usefulness of oral anticoagulation in patients with coronary aneurysms: Insights from the CAAR registry. Catheter Cardiovasc Interv. 2021 Nov 1;98(5):864-871. doi: 10.1002/ccd.29243. Epub 2020 Sep 9.

    PMID: 32902099RESULT

  • Arslan F, Nunez-Gil IJ, Rodriguez-Olivares R, Cerrato E, Bollati M, Nombela-Franco L, Terol B, Alfonso-Rodriguez E, Camacho Freire SJ, Villablanca PA, Amat Santos IJ, De la Torre Hernandez JM, Pascual I, Liebetrau C, Alkhouli M, Fernandez-Ortiz A; Coronary Artery Aneurysm Registry (CAAR) investigators. Sex differences in treatment strategy for coronary artery aneurysms: Insights from the international Coronary Artery Aneurysm Registry. Neth Heart J. 2022 Jun;30(6):328-334. doi: 10.1007/s12471-021-01649-5. Epub 2021 Dec 15.

    PMID: 34910278RESULT

MeSH Terms

Conditions

Coronary AneurysmHeart FailureAcute Coronary SyndromeDeath

Condition Hierarchy (Ancestors)

Coronary DiseaseMyocardial IschemiaHeart DiseasesCardiovascular DiseasesAneurysmVascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • IVAN J NUÑEZ GIL, MD,PhD,FESC

    HOSPITAL CLINICO SAN CARLOS.

    STUDY CHAIR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
12 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, PhD, FESC

Study Record Dates

First Submitted

September 26, 2015

First Posted

September 30, 2015

Study Start

September 1, 2015

Primary Completion

December 1, 2016

Study Completion

December 1, 2016

Last Updated

January 25, 2022

Record last verified: 2022-01

Locations

ES(1)