Efficacy of Periodontal Treatment on Glycaemic Control in Diabetic Patients
DIAPERIO
1 other identifier
interventional
91
1 country
2
Brief Summary
This study will assess the efficacy of periodontal treatment in diabetic patient. Patients will be randomized in the periodontal group or in the control group. The control group will received a periodontal treatment after the study.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable diabetes
Started Feb 2009
Longer than P75 for not_applicable diabetes
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2009
CompletedFirst Submitted
Initial submission to the registry
June 23, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2015
CompletedFirst Posted
Study publicly available on registry
September 30, 2015
CompletedDecember 15, 2025
November 1, 2018
6.5 years
June 23, 2015
December 5, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Hemoglobin A1c blood level
efficacy of periodontal treatment on hemoglobin A1c
3 months
Other Outcomes (2)
fructosamine blood level
3 weeks
Quality of life
3 months
Study Arms (2)
case
EXPERIMENTALdiabetic patients who will receive periodontal treatment blood sampling
control
EXPERIMENTALdiabetic patients without periodontal treatment (no periodontal treatment) blood sampling
Interventions
Eligibility Criteria
You may qualify if:
- patient suffering from a periodontitis
- patient with : 7,0% \< Hemoglobin A1c \< 9,5%
You may not qualify if:
- If an hospitalization is planned within the next 4 months
- Patient suffering from chronic infectious pathology (HIV, hepatitis C virus, hepatitis B virus, mononucleosis)
- Renal insufficiency
- Contra indication for amoxicilline or clindamycin
- Antithrombotic treatment
- Liver disease
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
UH Bordeaux
Bordeaux, 33000, France
UHToulouse
Toulouse, 31000, France
Related Publications (2)
Vergnes JN, Canceill T, Vinel A, Laurencin-Dalicieux S, Maupas-Schwalm F, Blasco-Baque V, Hanaire H, Arrive E, Rigalleau V, Nabet C, Sixou M, Gourdy P, Monsarrat P; DIAPERIO Group. The effects of periodontal treatment on diabetic patients: The DIAPERIO randomized controlled trial. J Clin Periodontol. 2018 Oct;45(10):1150-1163. doi: 10.1111/jcpe.13003. Epub 2018 Sep 14.
PMID: 30136741RESULTVergnes JN, Arrive E, Gourdy P, Hanaire H, Rigalleau V, Gin H, Sedarat C, Dorignac G, Bou C, Sixou M, Nabet C. Periodontal treatment to improve glycaemic control in diabetic patients: study protocol of the randomized, controlled DIAPERIO trial. Trials. 2009 Aug 2;10:65. doi: 10.1186/1745-6215-10-65.
PMID: 19646281RESULT
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Michel Sixou, MD
UH Toulouse
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 23, 2015
First Posted
September 30, 2015
Study Start
February 1, 2009
Primary Completion
August 1, 2015
Study Completion
August 1, 2015
Last Updated
December 15, 2025
Record last verified: 2018-11