NCT02554578

Brief Summary

The purpose of this study is to improve medication adherence, engagement and support to heart transplant patients through implementation of a new clinical care programme conducted by the clinical pharmacy service in cooperation with the heart transplant team and supported by mobile health (mHealth).

Trial Health

50
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
158

participants targeted

Target at P75+ for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 15, 2015

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 18, 2015

Completed
13 days until next milestone

Study Start

First participant enrolled

October 1, 2015

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2016

Completed
Last Updated

August 23, 2016

Status Verified

August 1, 2016

Enrollment Period

1.2 years

First QC Date

September 15, 2015

Last Update Submit

August 22, 2016

Conditions

Keywords

mHealthmultidisciplinary teamimmunosuppressive medicationpharmaceutical careadherenceheart transplantrecipients

Outcome Measures

Primary Outcomes (1)

  • Medication adherence measured on validated scales and questionnaires

    Change From Baseline in Medication Adherence on the Simplified Medication Adherence Questionnaire (SMAQ)

    6 months

Study Arms (2)

Pharmaceutical care programme supported by mHealth

EXPERIMENTAL
Other: Multidisciplinary follow-up programme supported by mHealth

Routine healthcare by the transplant team

NO INTERVENTION

Interventions

The follow-up programme integrates an online health platform (app and web) to monitor patients remotely, into the multidisciplinary team workflow, in order to improve heart transplant management. Patients will use the mobile application designed to help them to manage their health issues and facilitate communication with the transplant team. Data recorded manually by the patient using the mHealth application include pharmacotherapeutic information (medication adherence, barriers to adherence, side effects, interactions, etc.), clinical symptoms and other relevant clinical information (blood pressure, cardiac frequency, exercise, glucose level, diet, mood, etc.). mHealth will be used by the transplant team as a complementary way of deliver patient care. Analysis of the data collected by the multidisciplinary team may help to prioritise and provide personalized pharmacotherapeutic and medical interventions to patients and their families.

Also known as: Heart transplantation management by a multidisciplinary team and supported by mobile health (mHealth)
Pharmaceutical care programme supported by mHealth

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Heart transplant patients ≥ 18 years of age
  • Give informed consent.
  • Be able to use a mobile device (smartphone).
  • Sign a confidentiality agreement (interventional group).

You may not qualify if:

  • Non-available to receive a minimum of one-year clinical follow-up by the heart transplant unit.
  • Suffer severe mental disorders, other mental pathologies or conditions that can be a barrier to use the mobile application

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Mellon L, Doyle F, Hickey A, Ward KD, de Freitas DG, McCormick PA, O'Connell O, Conlon P. Interventions for increasing immunosuppressant medication adherence in solid organ transplant recipients. Cochrane Database Syst Rev. 2022 Sep 12;9(9):CD012854. doi: 10.1002/14651858.CD012854.pub2.

MeSH Terms

Interventions

Telemedicine

Intervention Hierarchy (Ancestors)

Delivery of Health CarePatient Care ManagementHealth Services Administration

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 15, 2015

First Posted

September 18, 2015

Study Start

October 1, 2015

Primary Completion

December 1, 2016

Last Updated

August 23, 2016

Record last verified: 2016-08