NCT02546973

Brief Summary

A national study of a three year cohort consisting of all patients diagnosed with anal cancer in 2011- 2013 with data retrieval from three national registries: Cancer Registry, Patient registry and Cause of Death Registry all within the Swedish Board of Health and Welfare. All out- and inpatient visits with diagnoses, admission dates and discharge dates will be requested including. Patient documentation from the concerned hospitals will be collected and data on the details of the treatment collected retrospectively in a standardised fashion using a clinical record form. Comorbidity will be calculated using data from the Patient Registry using all main and co-diagnoses 2 years prior and then at least two years after treatment cessation. Detailed questionnaires will be sent out once at 2-3 years and a second time at about 6 years after index treatment.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2015

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 26, 2015

Completed
6 days until next milestone

Study Start

First participant enrolled

September 1, 2015

Completed
10 days until next milestone

First Posted

Study publicly available on registry

September 11, 2015

Completed
8.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2024

Completed
Last Updated

December 8, 2023

Status Verified

December 1, 2023

Enrollment Period

8.7 years

First QC Date

August 26, 2015

Last Update Submit

December 7, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • HRQL in patient's with anal cancer 3 years after diagnosis

    To determine HRQL in patient's with anal cancer 3 years after diagnosis using a thorough questionnaire

    3 years

Secondary Outcomes (11)

  • HRQL in patient's with anal cancer 6 years after diagnosis Functional aspects and symptoms

    6 years

  • Comorbidity in the cohort prior to the diagnosis anal cancer

    3 years

  • Post-treatment morbidity in patients treated for anal cancer

    3 years

  • Type and number of surgical procedures in the patient population treated for anal cancer

    6 years

  • Accumulated length of hospital stay

    6 years

  • +6 more secondary outcomes

Study Arms (1)

Patients with anal cancer

All patients with anal cancer during 2011-2013 will be asked to participate

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with anal cancer diagnosed 2011-2013

You may qualify if:

  • All patients registered with a diagnosis of anal cancer in either the Patient registry or the Cancer Registry during 2011 - 2013.

You may not qualify if:

  • No informed consent received for participation in the questionnaire part of the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dept. of Surgery, Sahlgrenska University Hospital/Ostra

Gothenburg, SE 416 85, Sweden

Location

MeSH Terms

Conditions

Anus Neoplasms

Condition Hierarchy (Ancestors)

Rectal NeoplasmsColorectal NeoplasmsIntestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesIntestinal DiseasesAnus DiseasesRectal Diseases

Study Officials

  • Eva Angenete, M.D., Ph.D.

    Sahlgrenska University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
M.D., Ph.D., Ass. Prof.

Study Record Dates

First Submitted

August 26, 2015

First Posted

September 11, 2015

Study Start

September 1, 2015

Primary Completion

May 1, 2024

Study Completion

May 1, 2024

Last Updated

December 8, 2023

Record last verified: 2023-12

Data Sharing

IPD Sharing
Will not share

Locations