NCT02545270

Brief Summary

It is of great importance to obtain optimal surgical conditions for the surgeon in order to increase patient safety. The effect of different interventions on surgical conditions has been assessed by various surgeon-assessed rating scales. A 5-point surgical rating scale has previously been tested in a proof-of-concept trial - but not validated - during radical retropubic prostatectomy by asking different surgeons to evaluate the surgical workspace using video sequences. In an ongoing study (The Hernia Study, Trial registration NCT02247466) performed by investigators group, investigators are using a 5-point scale to rate the surgical workspace during laparoscopic ventral herniotomy with or without neuromuscular blockade. This scale is based on previously used scales by already published studies and has a description connected to each point. To the authors' knowledge the scale has never been validated in a laparoscopic setting, where the intra-abdominal pressure during pneumoperitoneum can have a great influence on visualization. In fact, to investigators knowledge, no validated surgeon-assessed rating scale regarding the surgical workspace during laparoscopic surgery does exists. Purpose: Primary aim: To validate a 5-point rating scale by investigating the inter-rater agreement of evaluations of the surgical workspace at different intra-abdominal pressures. Using intra-abdominal video recordings. Secondary aims: To validate a 10-point rating scale by investigating the inter-rater agreement of evaluations of the surgical workspace at different intra-abdominal pressures. To test the agreement between the two rating scales. To assess which of the two rating scales has the highest inter-rater agreement To assess the intra-rater agreement of both rating scales. Hypothesis: Investigators hypothesize that the 5-point rating scale has an intra-class correlation coefficient (ICC) \> 0.6., validated by video-sequences obtained during laparoscopic surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
16

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2016

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 6, 2015

Completed
1 month until next milestone

First Posted

Study publicly available on registry

September 9, 2015

Completed
6 months until next milestone

Study Start

First participant enrolled

March 1, 2016

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2016

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2016

Completed
2.9 years until next milestone

Results Posted

Study results publicly available

June 17, 2019

Completed
Last Updated

June 17, 2019

Status Verified

March 1, 2019

Enrollment Period

4 months

First QC Date

August 6, 2015

Results QC Date

March 20, 2018

Last Update Submit

March 18, 2019

Conditions

Keywords

Surgery, Laparoscopicsurgical rating scale

Outcome Measures

Primary Outcomes (1)

  • Inter-rater Agreement, 5-point Scale

    To validate a 5-point rating scale by investigating the inter-rater agreement of evaluations of the surgical workspace at different intra-abdominal pressures. The 5-point surgical rating scale is categorical, with following descriptions: 1 (Extremely poor conditions) Unable to complete surgery without interventions 2 (Poor conditions) Several minor adjustments needed to complete surgery. (e.g. changes in patient body position, surgeon position) 3 (Acceptable conditions) After few minor adjustments surgery can be completed. 4 (Good conditions) Surgical workspace is good, but there is some interference, but no need for adjustments. 5 (Optimal conditions) Surgical workspace is optimal and procedure can be completed without any interference. Using intra-abdominal video recordings. The inter-rater agreement will be calculated using intraclass correlation statistics with statistical software.

    60 min

Secondary Outcomes (3)

  • Inter-rater Agreement, 10-point Scale

    60 min

  • Agreement Between the Two Rating Scales Will be Tested With Regression Analysis Using Spearman Correlation Coefficient

    60 min

  • Intra-rater Agreement of Both Rating Scales.

    60 min

Study Arms (3)

Group 1: 12-9-6 mmHg

EXPERIMENTAL

Elective laparoscopic inguinal hernia procedures will be used to make three video-recordings (lasting 20-30 seconds) under different levels of pneumoperitoneum (12-9-6 mmHg) during desufflation after surgery is completed.

Procedure: Level of pneumoperitoneum 12-9-6 mmHg

Group 2: 11-8-5 mmHg

EXPERIMENTAL

Elective laparoscopic inguinal hernia procedures will be used to make three video-recordings (lasting 20-30 seconds) under different levels of pneumoperitoneum (11-8-5 mmHg) during desufflation after surgery is completed.

Procedure: Level of pneumoperitoneum 11-8-5 mmHg

Group 3: 10-7-4 mmHg

EXPERIMENTAL

Elective laparoscopic inguinal hernia procedures will be used to make three video-recordings (lasting 20-30 seconds) under different levels of pneumoperitoneum (10-7-4 mmHg) during desufflation after surgery is completed.

Procedure: Level of pneumoperitoneum 10-7-4 mmHg

Interventions

Elective laparoscopic inguinal hernia procedures will be used to make video-recordings under 3 different levels of pneumoperitoneum (12-9-6 mmHg) during desufflation.

Group 1: 12-9-6 mmHg

Elective laparoscopic inguinal hernia procedures will be used to make video-recordings under 3 different levels of pneumoperitoneum (11-8-5 mmHg) during desufflation.

Group 2: 11-8-5 mmHg

Elective laparoscopic inguinal hernia procedures will be used to make video-recordings under 3 different levels of pneumoperitoneum (10-7-4 mmHg) during desufflation.

Group 3: 10-7-4 mmHg

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients ≥ 18 years old
  • Elective laparoscopic inguinal herniotomy.
  • Can read and understand Danish

You may not qualify if:

  • Technical difficulties making video recording impossible.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Gentofte Hospital

Hellerup, Capital Region, 2900, Denmark

Location

Herlev Hospital

Copenhagen, Denmark

Location

MeSH Terms

Conditions

Hernia, Inguinal

Condition Hierarchy (Ancestors)

Hernia, AbdominalHerniaPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Results Point of Contact

Title
MD. G. G. Nervil
Organization
Department of Anesthesiology, Herlev and Gentofte Hospital, University of Copenhagen, Herlev Denmark

Study Officials

  • Roar Medici, MD

    Herlev Hospital University of Copenhagen

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Assistant, MD.

Study Record Dates

First Submitted

August 6, 2015

First Posted

September 9, 2015

Study Start

March 1, 2016

Primary Completion

July 1, 2016

Study Completion

August 1, 2016

Last Updated

June 17, 2019

Results First Posted

June 17, 2019

Record last verified: 2019-03

Locations