NCT02543684

Brief Summary

The aim of the current study was to compare the effects of three ready-to-eat mixed meals, with a high fiber content and low glycemic index, on postprandial glycemic and insulinemic response in patients with Type 2 diabetes mellitus (T2DM).

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for not_applicable diabetes-mellitus-type-2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2013

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2015

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

September 3, 2015

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 7, 2015

Completed
Last Updated

September 7, 2015

Status Verified

September 1, 2015

Enrollment Period

1.4 years

First QC Date

September 3, 2015

Last Update Submit

September 4, 2015

Conditions

Keywords

glycemic responsediabetesinsulinemic responsemixed mealsglycemic index

Outcome Measures

Primary Outcomes (2)

  • serum glucose changes over time

    fasting baseline glucose at time 0, then 30, 60, 90, and 120 minutes postprandial

  • serum insulin changes over time

    fasting baseline insulin at time 0, then 30, 60, 90, and 120 minutes postprandial

Study Arms (4)

ready to eat mixed meal 1

EXPERIMENTAL
Other: ready to eat mixed meal 1

ready to eat mixed meal 2

EXPERIMENTAL
Other: ready to eat mixed meal 2

ready to eat mixed meal 3

EXPERIMENTAL
Other: ready to eat mixed meal 3

oral glucose load

EXPERIMENTAL
Other: oral glucose load

Interventions

wild greens pie providing 50g of carbohydrates

Also known as: Sunday's Catering Company
ready to eat mixed meal 1

chicken burgers with boiled broccoli and cauliflower providing 50g of carbohydrates

Also known as: Sunday's Catering Company
ready to eat mixed meal 2

vegetable moussaka providing 50g of carbohydrates

Also known as: Sunday's Catering Company
ready to eat mixed meal 3

glucose load providing 50g of carbohydrates

oral glucose load

Eligibility Criteria

Age45 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Subjects are eligible if they are 45-75 years of age
  • non-insulin-dependent T2DM with an elapsed time since diagnosis of more than 3 years
  • Body Mass Index (BMI) value higher than 20 kg/m2
  • HbA1c levels of 6.5 to 11%

You may not qualify if:

  • insulin-dependent T2DM
  • cardiovascular (i.e. coronary heart disease, stroke etc.)
  • liver and/or renal disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Harokopio University of Athens

Kallithea, Attica, 17671, Greece

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 2Diabetes Mellitus

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Officials

  • Yannis Manios, Associate Professor

    Harokopio University, Athens

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

September 3, 2015

First Posted

September 7, 2015

Study Start

November 1, 2013

Primary Completion

April 1, 2015

Last Updated

September 7, 2015

Record last verified: 2015-09

Locations