NCT02542709

Brief Summary

The purpose of this trial is to study the effect of noninvasive brain stimulation in adults with post-traumatic stress disorder.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
28

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2015

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2015

Completed
25 days until next milestone

First Submitted

Initial submission to the registry

March 26, 2015

Completed
6 months until next milestone

First Posted

Study publicly available on registry

September 7, 2015

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2016

Completed
Last Updated

September 7, 2015

Status Verified

September 1, 2015

Enrollment Period

1 year

First QC Date

March 26, 2015

Last Update Submit

September 3, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Severity of symptoms on the following clinical scale: PTSD symptoms as assessed by the Modified PTSD Symptom Scale (MPSS-SR)

    Units will be the differences (%) in scores before and after the intervention

    2 months

Secondary Outcomes (2)

  • Severity of symptoms on the following clinical scale: anxiety symptoms as assessed by the Beck Anxiety Inventory (BAI)

    2 months

  • Severity of symptoms on the following clinical scale: depression symptoms as assessed by the Beck Depression Inventory (BDI)

    2 months

Study Arms (2)

Active transcranial magnetic stimulation

ACTIVE COMPARATOR

Active transcranial magnetic stimulation will induce real pulses using the transcranial magnetic stimulation device.

Device: Active repetitive Transcranial Magnetic Stimulation

Sham transcranial magnetic stimulation

SHAM COMPARATOR

Sham transcranial magnetic stimulation will not induce any pulses using the same transcranial magnetic stimulation device but by also adding a sham block device.

Device: Sham repetitive Transcranial Magnetic Stimulation

Interventions

Active transcranial magnetic stimulation will induce real pulses using the transcranial magnetic stimulation device.

Active transcranial magnetic stimulation

Sham transcranial magnetic stimulation will not induce any pulses using the same transcranial magnetic stimulation device but by also adding a sham block device.

Sham transcranial magnetic stimulation

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • years old

You may not qualify if:

  • Transcranial magnetic stimulation ineligibility

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

IRDPQ

Québec, Canada

RECRUITING

MeSH Terms

Conditions

Stress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Stress Disorders, TraumaticTrauma and Stressor Related DisordersMental Disorders

Central Study Contacts

Jean Levasseur-Moreau

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 26, 2015

First Posted

September 7, 2015

Study Start

March 1, 2015

Primary Completion

March 1, 2016

Study Completion

March 1, 2016

Last Updated

September 7, 2015

Record last verified: 2015-09

Locations