NCT02540044

Brief Summary

This proof-of-concept randomized trial evaluates the effectiveness of using an on-line decision aid (ANSWER-2) in the decision making to start or switch biologic therapy in Canadian patients with rheumatoid arthritis.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
148

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2016

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 1, 2015

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 3, 2015

Completed
4 months until next milestone

Study Start

First participant enrolled

January 1, 2016

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2018

Completed
Last Updated

June 29, 2017

Status Verified

June 1, 2017

Enrollment Period

2.9 years

First QC Date

September 1, 2015

Last Update Submit

June 27, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Decisional Conflict Scale

    The Decisional Conflict Scale (short version) measures personal perceptions of uncertainty in choosing options, factors contributing to uncertainty, and effective decision-making. It is one-dimensional and has 10 questions and three response categories (yes/no/unsure) used to compute one score.

    Change measure (baseline score compared to after using the ANSWER-2 intervention at month 1)

Secondary Outcomes (3)

  • MeiQ

    Change measure (baseline score compared to after using the ANSWER-2 intervention at month 1, and at month 2)

  • Partners in Health Scale

    Change measure (baseline score compared to after using the ANSWER-2 intervention at month 1, and at month 2)

  • Health Resource Utilization

    Change measure (baseline score compared to after using the ANSWER-2 at month 2)

Other Outcomes (1)

  • CollaboRATE Scale

    Change measure (baseline score compared to after using the ANSWER-2 intervention at month 1)

Study Arms (2)

ANSWER-2 decision aid

EXPERIMENTAL

The Intervention Group will receive simple instructions to access ANSWER-2 and complete the program on their own computers within two days. At the end of the session, ANSWER-2 will produce a one-page summary summarizing the participant's questions, concerns, and preferred medication option.

Behavioral: ANSWER-2 decision aid

Control Group (TAS Consumer Guide)

ACTIVE COMPARATOR

The Control Group will receive the online Arthritis Medications: A Consumer's Guide, published by The Arthritis Society. It contains standard information about biologics, including an introduction of the different biologic options, dosages and side effects.

Behavioral: Control Group (TAS Consumer Guide)

Interventions

ANSWER-2 will consist of: 1) an Information Module that presents effectiveness and side effects of each treatment option, and 2) an interactive Value Clarification Module that guides patients to consider what matter to them the most, and the pros and cons of each treatment option. Within the Information Module, the decision support information (i.e., the benefits and harms of treatment options) will be presented in narrated text, graphics, and a series of animated patient stories demonstrating attributes required for effective communication with doctors and significant others.

ANSWER-2 decision aid

The Arthritis Society Consumer guide pdf.

Control Group (TAS Consumer Guide)

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Arthritis Research Canada

Richmond, British Columbia, V6X2C7, Canada

RECRUITING

Related Links

MeSH Terms

Conditions

Arthritis, Rheumatoid

Interventions

Control Groups

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic DiseasesConnective Tissue DiseasesSkin and Connective Tissue DiseasesAutoimmune DiseasesImmune System Diseases

Intervention Hierarchy (Ancestors)

Epidemiologic Research DesignEpidemiologic MethodsInvestigative TechniquesResearch DesignMethods

Study Officials

  • Linda Li, PhD

    Professor

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

September 1, 2015

First Posted

September 3, 2015

Study Start

January 1, 2016

Primary Completion

December 1, 2018

Study Completion

December 1, 2018

Last Updated

June 29, 2017

Record last verified: 2017-06

Data Sharing

IPD Sharing
Will not share

Locations