NCT02539758

Brief Summary

Lowering intraocular pressure remains the mainstay of therapy in the management of glaucoma. The effect of ocular massage on intraocular pressure in patients with acute primary angle closure was the important thing.This was a prospective study, in which 20 eyes from 20 patients had acute angle closure. When they went to the hospital, ocular massage was performed without any medication. Intraocular pressure was detected by Goldmann tonometer, and Lenstar LS900 optical biometry observed changes of anterior chamber depth before and after ocular massage. Anterior chamber depth, anterior chamber angle and ciliary body were observed by Ultrasound biomicroscopy after massage, and anterior chamber angle was also checked by gonioscope after massage.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2013

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2013

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2014

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

August 8, 2015

Completed
26 days until next milestone

First Posted

Study publicly available on registry

September 3, 2015

Completed
Last Updated

September 3, 2015

Status Verified

August 1, 2015

Enrollment Period

1.2 years

First QC Date

August 8, 2015

Last Update Submit

August 31, 2015

Conditions

Keywords

acute angle closureocular massage

Outcome Measures

Primary Outcomes (1)

  • observed changes of anterior chamber depth before and after ocular massage

    before ocular massage and 15 minutes after massage

Secondary Outcomes (1)

  • observed changes of intraocular pressure before and after ocular massage

    before ocular massage and 15 minutes after massage

Study Arms (1)

ocular massage

EXPERIMENTAL

over the closed eyelids with moderate massage strength for 15 minutes. The compression of the globe was given with finger, and press for 2 seconds, then by a 2 seconds release, with a frequency of 15 presses/minute.We observed changes of anterior chamber depth before and after ocular massage by LenstarLS900,and changes of intraocular pressure before and after ocular massage by Goldmann tonometer

Other: ocular massageDevice: LenstarLS900Device: Goldmann tonometer

Interventions

ocular massage could be applied over the globe over the closed eyelids with moderate massage strength for 15 minutes. The compression of the globe was given with finger, and press for 2 seconds, then by a 2 seconds release, with a frequency of 15 presses/minute.

ocular massage

observed changes of anterior chamber depth before and after ocular massage by LenstarLS900

ocular massage

observed changes of intraocular pressure before and after ocular massage by Goldmann tonometer

ocular massage

Eligibility Criteria

Age45 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • All of them had documented evidence of acute angle closure.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tianjin Medical University Eye Hospital

Tianjin, Tianjin Municipality, 300384, China

Location

Study Officials

  • yingjuan Lv

    Tianjin Medical University Eye Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
department of ophthamology

Study Record Dates

First Submitted

August 8, 2015

First Posted

September 3, 2015

Study Start

July 1, 2013

Primary Completion

September 1, 2014

Study Completion

September 1, 2014

Last Updated

September 3, 2015

Record last verified: 2015-08

Locations