NCT02537756

Brief Summary

HPV vaccine coverage among adolescents in the US is suboptimal. This is particularly true among traditionally underserved adolescents. Few parent-targeted interventions have focused on the parental decision-making process. Self-persuasion, generating one's own arguments for engaging in a behavior, may be an effective means to influence parents' motivation to vaccinate their children. In a three-phase study, investigators are using quantitative and qualitative research methods to develop and refine a tablet-based self-persuasion intervention for parents who are undecided about the HPV vaccine. This clinical trial submission focuses on the second phase of the study. The results of the second phase will inform the third phase of the trial (also registered in clinical trials).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
737

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2016

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 26, 2015

Completed
7 days until next milestone

First Posted

Study publicly available on registry

September 2, 2015

Completed
7 months until next milestone

Study Start

First participant enrolled

April 5, 2016

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 26, 2018

Completed
1.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

October 26, 2019

Completed
Last Updated

May 18, 2020

Status Verified

May 1, 2020

Enrollment Period

2.3 years

First QC Date

August 26, 2015

Last Update Submit

May 14, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Survey Items Measuring Parental Intentions to vaccinate

    Change in intentions of the parent to vaccinate from baseline survey to exit survey using measures adapted from Gerend \& Shepherd (2012). Intentions Likert Scale responses range from 1-very likely to 5-very unlikely.

    During the intervention visit (1 hr)

Secondary Outcomes (2)

  • HPV vaccination behavior documented in the electronic medical record, initiation

    12 months

  • Change in Decision Stage

    During the intervention visit (1 hr)

Other Outcomes (3)

  • HPV vaccination behavior documented in the electronic medical record, completion

    15 months

  • Vaccination Concerns, qualitative

    During the intervention visit (1 hr)

  • Manipulation checks

    During the intervention visit (1 hr)

Study Arms (4)

1- Verbalize, Choice

EXPERIMENTAL

Parents will use a tablet-based application (Project Voice) that directs them to verbalize their own arguments based on topics they choose

Behavioral: Project Voice

2- Listen, Choice

EXPERIMENTAL

Parents will use a tablet-based application (Project Voice) that directs them to listen to peer-generated arguments based on topics they choose

Behavioral: Project Voice

3- Verbalize, Assigned

EXPERIMENTAL

Parents will use a tablet-based application (Project Voice) that directs them to verbalize their own arguments based on topics assigned to them

Behavioral: Project Voice

4- Listen, Assigned

EXPERIMENTAL

Parents will use a tablet-based application (Project Voice) that directs them to listen to peer-generated arguments based on topics assigned to them

Behavioral: Project Voice

Interventions

Project VoiceBEHAVIORAL

A tablet-based intervention that directs participants through different activities related to adolescent HPV vaccination based on their assigned condition

1- Verbalize, Choice2- Listen, Choice3- Verbalize, Assigned4- Listen, Assigned

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Undecided parents (18 years and older) whose children are 11-17 year old patients who have not begun the HPV vaccine series.

You may not qualify if:

  • Parents whose child is a pregnant adolescent
  • Lack telephone access
  • Having impairing hearing or speech
  • Participants will be excluded from participation in future stages

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UT Southwestern Medical Center

Dallas, Texas, 75390-8557, United States

Location

Related Publications (1)

  • Tiro JA, Lee SC, Marks EG, Persaud D, Skinner CS, Street RL, Wiebe DJ, Farrell D, Bishop WP, Fuller S, Baldwin AS. Developing a Tablet-Based Self-Persuasion Intervention Promoting Adolescent HPV Vaccination: Protocol for a Three-Stage Mixed-Methods Study. JMIR Res Protoc. 2016 Jan 29;5(1):e19. doi: 10.2196/resprot.5092.

Study Officials

  • Jasmin A Tiro, PhD

    University of Texas Southwestern Medical Center

    PRINCIPAL INVESTIGATOR
  • Austin S Baldwin, PhD

    Southern Methodist University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
CARE PROVIDER
Purpose
PREVENTION
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 26, 2015

First Posted

September 2, 2015

Study Start

April 5, 2016

Primary Completion

July 26, 2018

Study Completion

October 26, 2019

Last Updated

May 18, 2020

Record last verified: 2020-05

Data Sharing

IPD Sharing
Will share

Deidentified individual participant data (including data dictionaries) will be made available, in addition to study protocols, the statistical analysis plan, and the informed consent form. The data will be made available upon publication to researchers who provide a methodologically sound proposal and sign a data use agreement. Proposals should be submitted to Dr. Jasmin Tiro (jasmin.tiro@utsouthwestern.edu).

Shared Documents
STUDY PROTOCOL, SAP, ICF
Time Frame
January 2020, for 10 years
Access Criteria
Researchers who provide a methodologically sound proposal and sign a data use agreement. Proposals should be submitted to Dr. Jasmin Tiro (jasmin.tiro@utsouthwestern.edu).

Locations