NCT02530086

Brief Summary

A prospective randomized trial comparing non-operative management of small bowel obstruction due to adhesions with or without a naso-gastric tube (NGT).

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Aug 2015

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2015

Completed
16 days until next milestone

First Submitted

Initial submission to the registry

August 17, 2015

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 20, 2015

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 5, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 5, 2017

Completed
Last Updated

April 7, 2017

Status Verified

April 1, 2017

Enrollment Period

1.7 years

First QC Date

August 17, 2015

Last Update Submit

April 5, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Hospital length of stay

    Total hospital length of stay.

    30 days

Secondary Outcomes (3)

  • Pain measured on a visual analogue scale

    30 days

  • Duration of nasogastric decompression

    30 days

  • Number of radiographic studies ordered

    30 days

Study Arms (2)

Placement of a Nasogastric tube

ACTIVE COMPARATOR

Placement of a Nasogastric tube

Procedure: Nasogastric tube placement

No placement of a Nasogastric tube

EXPERIMENTAL

No placement of a Nasogastric tube

Procedure: No Nasogastric tube use

Interventions

Placement of a Nasogastric tube

Placement of a Nasogastric tube

No placement of a Nasogastric tube

No placement of a Nasogastric tube

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • All adult patients over 18 years of age who meet the following criteria will be recruited if identified:
  • Admitted to a general surgery service with a presumptive diagnosis of adhesive SBO with or without a history of abdominal surgery. Have had no abdominal surgery in the 30 days prior to enrollment.
  • Present from home or a long term care facility.
  • CT scan of the abdomen performed within 36 hours of admission consistent with small bowel obstruction and without evidence the obstruction is due to an incarcerated hernia, malignancy or volvulus.
  • Planned attempt at non-operative management by the attending surgeon.
  • Have the capacity to provide informed consent for themselves.

You may not qualify if:

  • Patient is deemed to need operative intervention at the time of presentation
  • Pregnancy
  • Contra-indication to NGT insertion
  • Presence of a gastric feeding tube or dependent on tube feeding or parenteral nutrition on admission.
  • Inability of the patient to protect their airway should emesis occur (as judged by the attending surgeon).
  • Intractable emesis on admission.
  • Abdominal surgery within 30 days prior to admission.
  • Patients transferred from an inpatient status at another acute care hospital will be excluded.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Yale New Haven Hospital

New Haven, Connecticut, 06510, United States

Location

Study Officials

  • Kevin M Schuster, MD, MPH

    Yale University

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 17, 2015

First Posted

August 20, 2015

Study Start

August 1, 2015

Primary Completion

April 5, 2017

Study Completion

April 5, 2017

Last Updated

April 7, 2017

Record last verified: 2017-04

Locations