NCT02527226

Brief Summary

This is a protocol to govern the prospective trial of facial nerve monitoring in patients undergoing parotidectomy with an eye towards interpreting if the facial nerve monitor provides useful information to operating surgeons and if the information provided by the facial nerve monitor can predict degrees of postoperative facial nerve paresis. Additionally, the study will determine if performing daily facial rehabilitation exercises provides a benefit in reducing time to recovery of temporary post-parotidectomy paresis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
76

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2015

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2015

Completed
16 days until next milestone

First Submitted

Initial submission to the registry

August 17, 2015

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 18, 2015

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2016

Completed
Last Updated

September 16, 2016

Status Verified

September 1, 2016

Enrollment Period

11 months

First QC Date

August 17, 2015

Last Update Submit

September 14, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Postoperative facial weakness

    Measure degree of facial weakness on postop day 1

    postoperative day 1

Secondary Outcomes (1)

  • Time to resolution of facial weakness

    3 months

Study Arms (2)

No facial exercises

NO INTERVENTION

This group will not receive any training in facial exercises.

Facial exercises

EXPERIMENTAL

This group will receive instruction to perform a series of self-administered exercises of facial expression and movements.

Behavioral: Facial exercises

Interventions

A series of self-administered facial movements and expressions.

Facial exercises

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years of age or older
  • Planned parotid gland surgery (superficial or total parotidectomy)
  • Benign or malignant disease

You may not qualify if:

  • Pregnancy
  • Preoperative facial nerve dysfunction
  • Revision operation
  • History of preoperative radiation to the surgical field
  • Entire nerve not dissected
  • Intentional nerve sacrifice
  • Poor signal to noise ratio during surgery
  • Lack of access to device compatible with video conferencing software, or lack of access to broadband internet connection

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Mayo Clinic in Arizona

Scottsdale, Arizona, 85259, United States

Location

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

Location

MeSH Terms

Conditions

Parotid NeoplasmsFacial Paralysis

Condition Hierarchy (Ancestors)

Salivary Gland NeoplasmsMouth NeoplasmsHead and Neck NeoplasmsNeoplasms by SiteNeoplasmsMouth DiseasesStomatognathic DiseasesParotid DiseasesSalivary Gland DiseasesParalysisNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Eric Moore, MD

    Mayo Clinic

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PI

Study Record Dates

First Submitted

August 17, 2015

First Posted

August 18, 2015

Study Start

August 1, 2015

Primary Completion

July 1, 2016

Study Completion

July 1, 2016

Last Updated

September 16, 2016

Record last verified: 2016-09

Locations