NCT02522039|Completed
Pupillary Response After Glaucoma Medication
pupil
Effect of Topical Anti-glaucoma Medications on Late Pupillary Light Reflex, as Evaluated by Pupillometry
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pupil
Effect of Topical Anti-glaucoma Medications on Late Pupillary Light Reflex, as Evaluated by Pupillometry
Sponsor study identifier
interventional
21
1 country
1
Study Start
May 2014
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
November 2014
Actual (reported)Study Completion
November 2014
Actual (reported)Investigation of the effect on the pupillary constriction by latanoprost, dorzolamide,timolol in healthy subjects. The pupillary constriction is compared to no drug.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
November 2014
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
May 2014
Date type not reportedThis date has not been verified as actual or estimated.
November 2014
Actual (reported)November 2014
Actual (reported)November 14, 2014
Actual (reported)August 13, 2015
Actual (reported)pupillary constriction measured as the post-illimination pupillay response (PIPR)
The pupillary diameter 0 to 10 seconds after light stimulation, the diameter is measured relative to the initial dark adapted pupil diameter
1 day
solution, 1 drop of 50ug/ml latanoprost, was given to study eye after washout period of 1 week between drugs
solution, 1 drop of 5mg/ml timolol , was given to study eye after washout period of 1 week between drugs
solution, 1 drop of 20 mg/ml dorzolamide, was given to study eye after washout period of 1 week between drugs
1 drop of latanoprost was given to study eye after washout period of 1 week between drugs
1 drop of timolol was given to study eye after washout period of 1 week between drugs
Glostrup University Hospital
Glostrup Municipality, DK-2600, Denmark
Henrik Lund-Andersen, Professor
Head of the project
21 participants (actual enrollment reported by the registry).
First Submitted
November 14, 2014
First Posted
August 13, 2015
Study Start
May 2014
Date type not reportedThis date has not been verified as actual or estimated.
Circadian Rhythms of Aqueous Humor Dynamics in Humans
no drug given and pupil measurements were performed before and at 30 and 180 min at equivalent hours as drugs measurements
1 drop of dorzolamide was given to study eye after washout period of 1 week between drugs
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Primary Completion
November 2014
Actual (reported)Study Completion
November 2014
Actual (reported)Last Updated
August 13, 2015
Record last verified: 2015-08
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Source: ClinicalTrials.gov.
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