The Effect of Various External Pressure on Blood
EPB
Comparison of the Effect of Various External Pressure on Blood During Rapid Infusion
1 other identifier
interventional
25
1 country
1
Brief Summary
Rapid infusion of blood is needed occasionally for control massive bleeding. For rapid infusion, external pressure can be used. The investigators will study correlation between external pressure and hemolysis and deformability of red blood cell.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Aug 2015
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2015
CompletedFirst Submitted
Initial submission to the registry
August 4, 2015
CompletedFirst Posted
Study publicly available on registry
August 13, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2015
CompletedNovember 30, 2015
November 1, 2015
3 months
August 4, 2015
November 25, 2015
Conditions
Outcome Measures
Primary Outcomes (1)
Hemolysis and alteration of deformability of red blood cell caused by external pressure
1hour
Study Arms (2)
5days
ACTIVE COMPARATOR5 days after blood sampling, various external pressure test will be done. Blood wil be stored in refrigerator(Celsius 4 degree) until study day. External pressure 0, 100, 150, 200, 250, 300mmHg will be applied to each blood sample.
35days
ACTIVE COMPARATOR35 days after blood sampling, various external pressure test will be done. Blood wil be stored in refrigerator(Celsius 4 degree) until study day. External pressure 0, 100, 150, 200, 250, 300mmHg will be applied to each blood sample.
Interventions
Blood pass through infusion set without external pressure.
Blood pass through infusion set under external pressure (150mmHg)
Blood pass through infusion set under external pressure (200mmHg)
Blood pass through infusion set under external pressure (250mmHg)
Blood pass through infusion set under external pressure (300mmHg)
Eligibility Criteria
You may qualify if:
- healthy volunteers, without any underlying disease.
You may not qualify if:
- history of delivery, abortion in past 6 months.
- weight : male under 50kg, female under 45kg
- heart rate under 50 or over 100
- fever : over 37.5
- blood pressure : over 180/100
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Hyub Huhlead
Study Sites (1)
Korea university anam hospital
Seoul, 136705, South Korea
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Hyub Huh, M.D.
Department of anesthesiology and pain medicine, Korea University Anam Hospital
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- INVESTIGATOR
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- M.D.
Study Record Dates
First Submitted
August 4, 2015
First Posted
August 13, 2015
Study Start
August 1, 2015
Primary Completion
November 1, 2015
Study Completion
November 1, 2015
Last Updated
November 30, 2015
Record last verified: 2015-11