NCT02519218

Brief Summary

The purpose of this study is to collect outcomes data in patients implanted with the Ellipse IM HTO Nail System.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
6

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Aug 2015

Typical duration for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2015

Completed
4 days until next milestone

First Submitted

Initial submission to the registry

August 5, 2015

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 10, 2015

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2017

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2017

Completed
Last Updated

February 1, 2018

Status Verified

January 1, 2018

Enrollment Period

2.2 years

First QC Date

August 5, 2015

Last Update Submit

January 30, 2018

Conditions

Outcome Measures

Primary Outcomes (2)

  • Target vs. Actual Correction

    Measured as either weight-bearing line (percent) or HKA angle (degrees)

    Participants will be followed for the duration of correcting their deformity, an average of 3 weeks

  • Target vs. Actual Correction

    Measured as either weight-bearing line (percent) or HKA angle (degrees)

    Participants will be followed for the duration of consolidation (bone healing), an average of 4 months

Secondary Outcomes (17)

  • Change in Weight-Bearing Line

    Participants will be followed for the duration of correcting their deformity, an average of 3 weeks

  • Change in Weight-Bearing Line

    Participants will be followed for the duration of consolidation (bone healing), an average of 4 months

  • Change in Weight-Bearing Line

    1-year post-operative

  • Change in Weight-Bearing Line

    2-years post-operative

  • Change in Hip-Knee-Ankle Angle

    Participants will be followed for the duration of correcting their deformity, an average of 3 weeks

  • +12 more secondary outcomes

Other Outcomes (4)

  • All Serious Adverse Events (SAEs) and Unanticipated Adverse Device Effects (UADEs)

    Participants will be followed through 2 years post-operative

  • All non-serious adverse events in the limb related to the device or study procedure. Study procedure includes implant procedure and correction lengthening procedure.

    Participants will be followed through 2 years post-operative

  • Secondary surgical procedures

    Participants will be followed through 2 years post-operative

  • +1 more other outcomes

Interventions

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients implanted with the Ellipse IM HTO Nail system for osteoarthritis and varus malalignment of the knee.

You may qualify if:

  • Patient implanted with the Ellipse IM HTO Nail System for osteoarthritis and varus malalignment of the knee
  • Patient signs informed consent for the use of their personal private data.

You may not qualify if:

  • Patient is currently enrolled in another clinical trial for high tibial osteotomy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Osteoarthritis

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Study Officials

  • Mark Dahl, MD

    University of Minnesota

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
OTHER
Target Duration
2 Years
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 5, 2015

First Posted

August 10, 2015

Study Start

August 1, 2015

Primary Completion

October 1, 2017

Study Completion

December 1, 2017

Last Updated

February 1, 2018

Record last verified: 2018-01