NCT02514876

Brief Summary

This study will evaluate the efficacy of 2D forward-looking and 3D Intracardiac Echocardiography (ICE) to guide septal punctures during Atrial Fibrillation ablation procedures.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for early_phase_1

Timeline
Completed

Started Sep 2015

Shorter than P25 for early_phase_1

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 27, 2015

Completed
8 days until next milestone

First Posted

Study publicly available on registry

August 4, 2015

Completed
28 days until next milestone

Study Start

First participant enrolled

September 1, 2015

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 8, 2016

Completed
27 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 5, 2016

Completed
Last Updated

April 24, 2017

Status Verified

April 1, 2017

Enrollment Period

7 months

First QC Date

July 27, 2015

Last Update Submit

April 21, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Successful transseptal puncture during atrial fibrillation ablation procedure under the guidance of study device

    During ablation procedure (2-4 h)

Study Arms (1)

Single arm- Foresight ICE System

EXPERIMENTAL

This open label feasibility study will evaluate the Foresight ICE system for imaging chambers of the heart and guiding transseptal puncture during an atrial fibrillation (AF) ablation procedure.

Device: Foresight ICE System

Interventions

The Foresight ICE System is composed of a sterile, single-use catheter intended to operate with a Foresight ICE PIM and Hummingbird Console.

Single arm- Foresight ICE System

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient is at least 18 years old.
  • Patient is undergoing an atrial fibrillation ablation procedure.
  • Patient has a transesophageal echocardiogram (TEE) within the 48 hours prior to ablation procedure to rule out left atrial thrombus.
  • Patient provides informed, written consent for participation in the study.

You may not qualify if:

  • Patients in whom placement of an ICE catheter in the right atrium for adequate atrial visualization is not technically feasible (as evaluated and determined by the physician performing the procedure).
  • Patients in whom transseptal puncture is relatively contraindicated.
  • Patients in whom left atrial clot or dense spontaneous contrast is identified on TEE, which would increase thromboembolic risk.
  • Women of child bearing potential, in whom pregnancy cannot be excluded.
  • Patients unable to grant informed, written consent for participation in the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Southlake Regional Health Centre

Newmarket, Ontario, L3Y2P6, Canada

Location

MeSH Terms

Conditions

Atrial Fibrillation

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacHeart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Atul Verma, MD

    Southlake Regional Health Centre

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
early phase 1
Allocation
NA
Masking
NONE
Purpose
DEVICE FEASIBILITY
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 27, 2015

First Posted

August 4, 2015

Study Start

September 1, 2015

Primary Completion

April 8, 2016

Study Completion

May 5, 2016

Last Updated

April 24, 2017

Record last verified: 2017-04

Locations