The Effect of Thermotherapy on Recovery and Performance
Cryotherapy
The Effect of Cryotherapy on Recovery and Performance: A Randomized Controlled Double Blind Trial
1 other identifier
interventional
22
1 country
1
Brief Summary
This study investigates the effects of cooling on the recovery and performance characteristic in young healthy subjects. The study is divided in two projects: Project A: investigates the effects of 20 min. post-exercise cooling on vertical jump performance and delayed onset muscle soreness and rated perceived exertion. Project B: investigates the effects of 20 min. pre-exercise cooling on maximal voluntary contraction of the right M. quadriceps femoris and delayed onset muscle soreness and rated perceived exertion.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable healthy
Started May 2015
Longer than P75 for not_applicable healthy
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2015
CompletedFirst Submitted
Initial submission to the registry
May 27, 2015
CompletedFirst Posted
Study publicly available on registry
July 23, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2019
CompletedResults Posted
Study results publicly available
October 20, 2025
CompletedOctober 20, 2025
September 1, 2025
3.5 years
May 27, 2015
September 30, 2025
September 30, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (4)
Delayed-onset Muscle Soreness (DOMS)
The subjective recovery characteristics "Delayed-onset muscle soreness (DOMS)" was rated on a 0-10 cm visual analog scale. DOMS was assessed in a squat position (90° knee angle, with brief holding of maximum 3 seconds) ranging from zero (no soreness) to ten (severe soreness). Higher values mean mean more DOMS and therefore less recovery.
72 hours
Ratings of Perceived Exertion (RPE)
The subjective recovery characteristics " Ratings of perceived exertion (RPE)" was rated on a 6-20 Borg scale (from 6 = "no exertion at all" to 20 = "Maximal exertion") in a standing position. The higher value means more exertion and therefore less recovery.
72 hours
Vertical Jump Performance (VJP)
Vertical jump performance (VJP) was assessed performing three maximal counter mouvemet jumps (CMJs) with a 30-second pause between the three jumps on the Just Jump system (Probotics Inc, Huntsville, AL, USA). The highest jump was recorded.
72 hours
Peak Power Output (PPO)
Peak power output (PPO) was assessed performing three maximal counter movement jumps (CMJs) on the Just Jump system (Probotics Inc, Huntsville, AL, USA) with a 30-second pause between the three jumps. PPO (presented in watts) was calculated.
72 hours
Study Arms (2)
cooling intervention
EXPERIMENTALsubjects in this study receive a single pre-exercise (3x MVC) or post-exercise intervention (3x 30 counter movement jumps), consisting of an external cooling application (Zamar Therapy CT clinic) applied to both thighs. Both interventions have a duration of 20 minutes and a temperature of 8°C
thermoneutral intervention
SHAM COMPARATORsubjects in the control group receive a single pre-exercise (3x MVC) or post-exercise (3x 30 counter movement jumps) sham intervention, consisting of a 20 minute external thermoneutral application (Zamar Therapy CT clinic) applied to both thighs. Both sham interventions have a duration of 20 minutes and a temperature of 32°C.
Interventions
Zamar Therapy is a certified medical product (directive 93/42/EEC and ISO 134 85:2012) (www.zamarmedical.com)
Eligibility Criteria
You may qualify if:
- only healthy young subjects 18-30 years
- no musculoskeletal surgery in trunk and lower extremities
- injury history in trunk and lower extremity for more than one year
- subjects taking anticonceptive medication are allowed to participate
You may not qualify if:
- actual injuries or injuries for less than one year in trunk and /or lower extremities
- injury history in trunk and lower extremity for more than one year with complaints
- anxiety of cooling
- subjects on medication
- pace maker
- cardiovascular disease
- pregnancy
- skeletal problems
- appendectomy for less than two years
- Morbus Raynaud syndrome
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Applied Sciences and Arts of Southern Switzerland SUPSI
Landquart, Kanton Graubünden, 7302, Switzerland
Related Publications (8)
Bleakley C, McDonough S, Gardner E, Baxter GD, Hopkins JT, Davison GW. Cold-water immersion (cryotherapy) for preventing and treating muscle soreness after exercise. Cochrane Database Syst Rev. 2012 Feb 15;2012(2):CD008262. doi: 10.1002/14651858.CD008262.pub2.
PMID: 22336838BACKGROUNDRoss ML, Garvican LA, Jeacocke NA, Laursen PB, Abbiss CR, Martin DT, Burke LM. Novel precooling strategy enhances time trial cycling in the heat. Med Sci Sports Exerc. 2011 Jan;43(1):123-33. doi: 10.1249/MSS.0b013e3181e93210.
PMID: 20508537BACKGROUNDAscensao A, Leite M, Rebelo AN, Magalhaes S, Magalhaes J. Effects of cold water immersion on the recovery of physical performance and muscle damage following a one-off soccer match. J Sports Sci. 2011 Feb;29(3):217-25. doi: 10.1080/02640414.2010.526132.
PMID: 21170794RESULTBanfi G, Lombardi G, Colombini A, Melegati G. Whole-body cryotherapy in athletes. Sports Med. 2010 Jun 1;40(6):509-17. doi: 10.2165/11531940-000000000-00000.
PMID: 20524715RESULTBarnett A. Using recovery modalities between training sessions in elite athletes: does it help? Sports Med. 2006;36(9):781-96. doi: 10.2165/00007256-200636090-00005.
PMID: 16937953RESULTPointon M, Duffield R, Cannon J, Marino FE. Cold application for neuromuscular recovery following intense lower-body exercise. Eur J Appl Physiol. 2011 Dec;111(12):2977-86. doi: 10.1007/s00421-011-1924-1. Epub 2011 Mar 29.
PMID: 21445604RESULTWegmann M, Faude O, Poppendieck W, Hecksteden A, Frohlich M, Meyer T. Pre-cooling and sports performance: a meta-analytical review. Sports Med. 2012 Jul 1;42(7):545-64. doi: 10.2165/11630550-000000000-00000.
PMID: 22642829RESULTWhite GE, Wells GD. Cold-water immersion and other forms of cryotherapy: physiological changes potentially affecting recovery from high-intensity exercise. Extrem Physiol Med. 2013 Sep 1;2(1):26. doi: 10.1186/2046-7648-2-26.
PMID: 24004719RESULT
Related Links
Results Point of Contact
- Title
- Dr. Erich Hohenauer
- Organization
- University of Applied Sciences and Arts of Southern Switzerland (SUPSI)
Study Officials
- PRINCIPAL INVESTIGATOR
Ron Clijsen, PhD
University of Applied Sciences and Arts of Southern Switzerland SUPSI
Publication Agreements
- PI is Sponsor Employee
- Yes
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 27, 2015
First Posted
July 23, 2015
Study Start
May 1, 2015
Primary Completion
November 1, 2018
Study Completion
May 1, 2019
Last Updated
October 20, 2025
Results First Posted
October 20, 2025
Record last verified: 2025-09