Interval Training in Bipolar Disorder
HIIT
Can the High Intensity Interval Training (HIIT) Deliver Superior and Rapid Decrease of Symptoms of Bipolar Disorder? a Controlled and Randomized Study
1 other identifier
interventional
36
1 country
1
Brief Summary
Our main objective will be to evaluate the chronic effects (12 weeks) of high-intensity interval training compared to moderate intensity (same total work) on reducing the symptoms of bipolar disorder, cortical changes, as well as on the VO2max. In addition, the investigators will establish what influence of gain to VO2max has on reducing symptoms.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Aug 2015
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 11, 2015
CompletedFirst Posted
Study publicly available on registry
July 15, 2015
CompletedStudy Start
First participant enrolled
August 1, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2017
CompletedJuly 29, 2022
July 1, 2022
1.9 years
July 11, 2015
July 27, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Symptom Scales (Hamilton and Young)
Variable Measured to reduction of symptoms
0 week, 6 week, 12 week
Secondary Outcomes (3)
Cortical Changes (EEG) - Loreta
0 week, 6 week, 12 week
VO2Max
0 week, 6 week, 12 week
Cognitive Function
0 week, 6 week, 12 week
Study Arms (3)
Interval Training
ACTIVE COMPARATOR6 stimulous (30 s) at 100% VO2Max/ 1 min 30 s to rest, 19 minutes (total exercise), 3 times/ week, 12 weeks
Continuous Training
ACTIVE COMPARATORRunning at 60% VO2Max, 25 minutes (total exercise), 3 times/week, 12 weeks
Control
SHAM COMPARATOROnly Dependent Variables Measures
Interventions
High Intensity Interval Training at 100% VO2Max
Continuous Stimulous at 60% VO2Max
Eligibility Criteria
You may qualify if:
- Bipolar Criteria (DSM-IV),
- sedentary lifestyle
You may not qualify if:
- and over,
- Cardiovascular Disease,
- Panic disorder,
- Metabolic syndrome Diagnosis
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Institute of Psychiatry (IPUB)
Rio de Janeiro, Brazil
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Sérgio E. Machado, PhD
Universidade Federal do Rio de Janeiro
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Doctorade in Mental Health
Study Record Dates
First Submitted
July 11, 2015
First Posted
July 15, 2015
Study Start
August 1, 2015
Primary Completion
July 1, 2017
Study Completion
July 1, 2017
Last Updated
July 29, 2022
Record last verified: 2022-07