NCT02496130

Brief Summary

The goal of this study is to compare common methods of tissue extraction at the time of minimally invasive surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Apr 2016

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 9, 2015

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 14, 2015

Completed
9 months until next milestone

Study Start

First participant enrolled

April 1, 2016

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2017

Completed
Last Updated

January 25, 2019

Status Verified

January 1, 2019

Enrollment Period

1.4 years

First QC Date

July 9, 2015

Last Update Submit

January 23, 2019

Conditions

Keywords

minilaparotomymorcellationlaparoscopy

Outcome Measures

Primary Outcomes (1)

  • Return to daily activities

    Return to daily activities will be recorded on a post-operative patient activity diary recording the following tasks: a) work (if applicable), b) domestic tasks, c) driving a vehicle (if applicable) and d) physical exercise (if applicable).

    assessed between 2 and 6 weeks after surgery (at post-op visit)

Secondary Outcomes (3)

  • OR Time

    At the time of surgery

  • Estimated Blood Loss

    At the time of surgery

  • Spillage of the morcellated tissue or fluids in the abdomen and pelvis

    At the time of surgery

Study Arms (2)

minilaparotomy

Subjects in this group will have tissue (uterus) extracted via mini-laparotomy incision with knife morcellation. Morcellation will be performed within a containment system. Method of extraction/group assignment will be determined clinically by the operating surgeon based on patient characteristics and patient preference.

vaginal extraction

Subjects in this group will have tissue (uterus) extracted via vaginal extraction with knife morcellation. Morcellation will be performed within a containment system. Method of extraction/group assignment will be determined clinically by the operating surgeon based on patient characteristics and patient preference.

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

70 adult women scheduled to undergo a laparoscopic hysterectomy

You may qualify if:

  • years of age or greater
  • eligible to undergo laparoscopic Hysterectomy, as determined clinically by the operating surgeon

You may not qualify if:

  • suspected malignancy
  • medical illness precluding laparoscopy
  • inability to give informed consent
  • allergy to indigo carmine or methylene blue dye

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Massachusetts General Hospital

Boston, Massachusetts, 02114, United States

Location

Brigham & Women's Hospital

Boston, Massachusetts, 02115, United States

Location

Faulkner Hospital

Boston, Massachusetts, 02130, United States

Location

Study Officials

  • Jon I Einarsson, MD, PhD, MPH

    Brigham and Women's Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Chief, Division of Minimally Invasive Gynecology

Study Record Dates

First Submitted

July 9, 2015

First Posted

July 14, 2015

Study Start

April 1, 2016

Primary Completion

September 1, 2017

Study Completion

September 1, 2017

Last Updated

January 25, 2019

Record last verified: 2019-01

Data Sharing

IPD Sharing
Will not share

Locations