NCT02486107

Brief Summary

In case of cervical foraminal stenosis without central stenosis, there are several options; anterior discectomy and fusion (ACDF), tubular retractor assisted micro-foraminotomy (MTPF) and posterior percutaneous cervical foraminotomy and discectomy (P-PECD). P-PECD is a modern technique and there was no RCT with MTPF, although P-PECD showed not inferior result to ACDF. Nowadays MTPF and P-PECD are minimally invasive surgical techniques, but there was no comparative study. The primary object of the study is to compare radiological outcome (segment angle) after MTPF or P-PECD.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
156

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started May 2015

Longer than P75 for all trials

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2015

Completed
19 days until next milestone

First Submitted

Initial submission to the registry

May 20, 2015

Completed
1 month until next milestone

First Posted

Study publicly available on registry

July 1, 2015

Completed
4.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2019

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2020

Completed
Last Updated

April 18, 2024

Status Verified

April 1, 2024

Enrollment Period

4.6 years

First QC Date

May 20, 2015

Last Update Submit

April 16, 2024

Conditions

Keywords

cervical vertebrasurgerytubular retractorendoscope

Outcome Measures

Primary Outcomes (1)

  • change of segmental angle

    postoperative 1 year

Secondary Outcomes (4)

  • operation time

    postoperative 1 year

  • neck/arm pain

    postop 1 year

  • neck disability, index

    postop 1 year

  • cervical curvature

    postop 1 year

Study Arms (3)

PECD

percutaneous endoscopic cervical foraminotomy

Procedure: surgical procedure

MTPF

microscopic tubular retractor assisted foraminotomy

Procedure: surgical procedure

ACDF

anterior cervical discectomy and fusion

Procedure: surgical procedure

Interventions

ACDFMTPFPECD

Eligibility Criteria

Age20 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Alpha = 0.05, Beta = 0.2, q1 = 0.5, effect size = 0.6 drop rate 12% 52 patients in each group

You may qualify if:

  • cervical radicular pain
  • no cervical myelopathy

You may not qualify if:

  • motor weakness less than MMT Gr III
  • cervical myelopathy
  • OPLL and myelopathy
  • previous cervical spine surgery
  • combined fracture or spinal tumor

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Kyoung-Pook National University Hospital

Seoul, Province, 03080, South Korea

Location

Seoul National University Bundang Hospital

Seoul, 03080, South Korea

Location

Seoul National University Hospital

Seoul, 110-744, South Korea

Location

MeSH Terms

Conditions

Spinal Curvatures

Interventions

Surgical Procedures, Operative

Condition Hierarchy (Ancestors)

Spinal DiseasesBone DiseasesMusculoskeletal Diseases

Study Officials

  • Chun Kee Chung, Professor

    Seoul National University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
professor

Study Record Dates

First Submitted

May 20, 2015

First Posted

July 1, 2015

Study Start

May 1, 2015

Primary Completion

December 1, 2019

Study Completion

December 1, 2020

Last Updated

April 18, 2024

Record last verified: 2024-04

Locations