Interest in the Use of Dressings With Honey for Wound Healing After Excision of Pilonidal Cyst

NCT02485860 | Completed Phase 4 Results

• 1 other identifier: CHD018-15
• Study Type: interventional
• Target: 890
• Locations: 1 country
• Sites: 1

Brief Summary

The management of pilonidal cysts is a skin excision and under deep skin. Scarring requires regular dressings (daily for 15 days and then every 48 hours) until complete healing. This healing is obtained on average in 68 days. Some patients have difficulties in healing with a final healing achieved on average in 95 days. Some teams use honey to promote wound cavitary wounds (wound infection, pressure ulcers, varicose wound). The acceleration of wound healing is due to antibacterial properties and hyperosmolarity to reduce secretions. ) The use of honey in pilonidal cysts is not evaluated and may accelerate healing.

Conditions

Pilonidal Cysts

Keywords

pilonidal cysts; Cavity wound; long healing; honey

Outcome Measures

Primary Outcomes (1)

• Healing Time

  from randomization to 180 days maximum

Study Arms (2)

standard dressings

NO INTERVENTION

In general, the dressings made are either of the type : * Algosteril® (round or flat wick) + Mepilex® border * or AquacelTM ExtraTM + AquacelTM Foam

standard dressings with sterile honey

EXPERIMENTAL

Melectis G

Device: Melectis G

Interventions

Melectis G DEVICE

standard dressings with sterile honey

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Cavity Wound to 6 weeks of a pilonidal cyst excision
• Bloodless wound
• Pilonidal cyst not recurred
• Age : 18 years and older
• Signature of informed consent
• In the capacity to understand the study

You may not qualify if:

• Bleeding wound
• Refused to participate in Protocol
• Patient immunocompromised
• Recurrent pilonidal cyst
• Patients on long-term corticosteroid
• Patient deprived of liberty, under guardianship
• Patient unable to understand the study
• Allergy or hypersensitivity to honey
• Allergy Or hypersensitivity to hyaluronic acid
• Allergy or hypersensitivity to guar gum
• Allergy or hypersensitivity to pectin
• Known allergy to propolis (potentially present in honey)
• Sensitivity to zinc oxide
• Sensitivity known dressings used in this trial or any component
• Diabetes Non-insulin or insulin

Sponsors & Collaborators

• Centre Hospitalier Departemental Vendee: lead

Study Sites (1)

Centre Hospitalier Departemental Vendée

La Roche-sur-Yon, 85925, France

Location

Related Publications (1)

• Abet E, Jean MH, Greilsamer T, Planche L, Maurice F, Brau-Weber AG, Denimal F. The value of honey dressings in pilonidal cyst healing: a prospective randomized single-center trial. Tech Coloproctol. 2023 Sep;27(9):721-727. doi: 10.1007/s10151-022-02740-8. Epub 2023 Jan 4.

  PMID: 36598614 RESULT

MeSH Terms

Conditions

Pilonidal Sinus

Condition Hierarchy (Ancestors)

Cysts; Neoplasms

Results Point of Contact

• Title: Dr. Emeric ABET
• Organization: Centre Hospitalier Departemental Vendée

emeric.abet@ght85.fr

02 51 44 61 48

Study Officials

• Emeric ABET, PH

  Centre Hospitalier Departemental Vendee

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: interventional
• Phase: phase 4
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 26, 2015
• First Posted: June 30, 2015
• Study Start: March 8, 2016
• Primary Completion: February 10, 2022
• Study Completion: February 10, 2022
• Last Updated: December 2, 2025
• Results First Posted: October 25, 2023

Record last verified: 2025-11

Locations

FR (1)