The Lolland-Falster Health Study
LOFUS
1 other identifier
observational
25,000
1 country
1
Brief Summary
The study is a epidemiological, cross-sectional study in a mainly rural area of Denmark in Denmark. Life expectancy is shorter, morbidity is higher, and social problems more prevalent than in the urban areas of the country. The population study aims at examining complexities of environmental, hereditary, lifestyle, and social factors as determinants and predisposing factors for morbidity, health, and quality of life. The study will cover physical, mental, and social dimensions and examine family patterns and subgroups. The study will provide baseline information for later follow-up.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Feb 2016
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 1, 2015
CompletedFirst Posted
Study publicly available on registry
June 26, 2015
CompletedStudy Start
First participant enrolled
February 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2019
CompletedOctober 7, 2016
June 1, 2016
3.8 years
June 1, 2015
October 6, 2016
Conditions
Outcome Measures
Primary Outcomes (1)
Health
Self-administered questionnaires, clinical examination, and biospecimen
Cross-sectional, measured once
Secondary Outcomes (2)
Morbidity
Cross-sectional, measured once
Risk factors
Cross-sectional, measured once
Eligibility Criteria
The population of Lolland and Guldborgsund municipalities in Denmark.
You may qualify if:
- Individuals registered in Lolland or Guldborgsund municipality
You may not qualify if:
- Adults with incapacity guardianship
- Incapacity to give informed consent
- Individuals with address protection
- Severe physical immobility
- Non-Danish and Non-English speaking
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Region Sjællandlead
- Lolland Municipality, Denmarkcollaborator
- Guldborgsund Municipality, Denmarkcollaborator
Study Sites (1)
The Lolland-Falster Health Study
Nykøbing Falster, Region Sjælland, 4800, Denmark
Related Publications (8)
Mortensen SR, Brond JC, Petersen TL, Jepsen R, Dominguez-Navarro F, Skou ST, Grontved A. Association of Device-Measured Habitual Sedentary Activity and Standing Posture With Blood Pressure and Hypertension in Danish Adults: The Lolland-Falster Health Study. J Am Heart Assoc. 2025 Aug 19;14(16):e039133. doi: 10.1161/JAHA.124.039133. Epub 2025 Aug 18.
PMID: 40820973DERIVEDBruun-Rasmussen NE, Napolitano G, Bojesen SE, Ellervik C, Holmager TLF, Rasmussen K, Lynge E. Correlation between allostatic load index and cumulative mortality: a register-based study of Danish municipalities. BMJ Open. 2024 Feb 12;14(2):e075697. doi: 10.1136/bmjopen-2023-075697.
PMID: 38346879DERIVEDMortensen SR, Skou ST, Brond JC, Ried-Larsen M, Petersen TL, Jorgensen LB, Jepsen R, Tang LH, Bruun-Rasmussen NE, Grontved A. Detailed descriptions of physical activity patterns among individuals with diabetes and prediabetes: the Lolland-Falster Health Study. BMJ Open Diabetes Res Care. 2023 Sep;11(5):e003493. doi: 10.1136/bmjdrc-2023-003493.
PMID: 37699719DERIVEDGronlund C, Djurhuus BD, Holm EA, Homoe P. Self-reported dizziness, falls, and self-rated health in a rural population in Denmark. Eur Arch Otorhinolaryngol. 2023 Dec;280(12):5329-5337. doi: 10.1007/s00405-023-08061-2. Epub 2023 Jul 8.
PMID: 37420013DERIVEDSondergaard E, Reventlow S, Siersma V, Nicolaisdottir DR, Jepsen R, Rasmussen K, Moller A. A cross-sectional study of the association between family conflicts and children's health: Lolland-Falster Health Study. Child Care Health Dev. 2023 Nov;49(6):972-984. doi: 10.1111/cch.13108. Epub 2023 Feb 28.
PMID: 36805605DERIVEDPetersen TL, Brond JC, Kristensen PL, Aadland E, Grontved A, Jepsen R. Resemblance in Physical Activity in Families with Children in Time Segments during the Week: The Lolland-Falster Health Study. Med Sci Sports Exerc. 2021 Nov 1;53(11):2283-2289. doi: 10.1249/MSS.0000000000002718.
PMID: 34107506DERIVEDJacobsen KK, Jepsen R, Lembeck MA, Nilsson C, Holm E. Associations between the SHARE frailty phenotype and common frailty characteristics: evidence from a large Danish population study. BMJ Open. 2019 Oct 15;9(10):e032597. doi: 10.1136/bmjopen-2019-032597.
PMID: 31619433DERIVEDJepsen R, Egholm CL, Brodersen J, Simonsen E, Grarup J, Cyron A, Ellervik C, Rasmussen K. Lolland-Falster Health Study: Study protocol for a household-based prospective cohort study. Scand J Public Health. 2020 Jun;48(4):382-390. doi: 10.1177/1403494818799613. Epub 2018 Sep 17.
PMID: 30222051DERIVED
Biospecimen
Blood, urine, faeces, saliva
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Knud Rasmussen, Dr. Med., MD
Region Sjælland
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- FAMILY BASED
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 1, 2015
First Posted
June 26, 2015
Study Start
February 1, 2016
Primary Completion
December 1, 2019
Study Completion
December 1, 2019
Last Updated
October 7, 2016
Record last verified: 2016-06