NCT02481986

Brief Summary

The Asthma Action at Erie Trial compares the current best practice in asthma self-management education (certified asthma educator services) to an integrated community health worker (CHW) home intervention in which the real-life challenges of patients and the health care system are taken fully into account. This trial will provide clarity as to the expected effect size, cost savings, and resources needed to integrate asthma CHWs into clinical practice.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
223

participants targeted

Target at P25-P50 for phase_3 asthma

Timeline
Completed

Started Apr 2015

Longer than P75 for phase_3 asthma

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2015

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

June 5, 2015

Completed
20 days until next milestone

First Posted

Study publicly available on registry

June 25, 2015

Completed
4.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2020

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2021

Completed
8 months until next milestone

Results Posted

Study results publicly available

December 9, 2021

Completed
Last Updated

December 9, 2021

Status Verified

November 1, 2021

Enrollment Period

5 years

First QC Date

June 5, 2015

Results QC Date

July 22, 2021

Last Update Submit

November 11, 2021

Conditions

Outcome Measures

Primary Outcomes (2)

  • Asthma Control Test/Childhood Asthma Control Test at 12-months

    Asthma Control Test (12 years or older) or Childhood Asthma Control Test (under 12 years old) minimum 5, maximum 27, higher score means better asthma control

    assessed 12-months from baseline, assessed over past 4 weeks

  • Activity Limitation at 12-months

    Days of activity limitation over past 14 days minimum 0, maximum 14, higher means worse asthma control

    assessed 12-months after baseline, assessed over past 14 days

Secondary Outcomes (3)

  • Asthma Control Questionnaire at 12-months

    assessed 12-months after baseline, prior week assessed

  • Health Care Utilization at 12-months

    assessed 12-months after baseline, assessed from baseline to 12-months

  • Costs of Intervention Delivery

    assessed 12-months from baseline, assessed from baseline to 12-months

Study Arms (2)

Community health worker

EXPERIMENTAL

Participants in this arm will be offered 10 home visits in a 12-month period from community health workers (CHWs). Visits will cover a core asthma curriculum and provide social support.

Behavioral: Community Health Worker

Certified asthma educator

ACTIVE COMPARATOR

Participants in this arm will be offered 2 education sessions with a certified asthma educator in the clinic at start of the study and again at 6-months. These sessions will be followed by a telephone call from the certified asthma educator several weeks after the sessions.

Behavioral: Certified asthma educator

Interventions

A community health worker is para-professional who performs education, case management, and social support.

Community health worker

A certified asthma educator has is certified and performs asthma education.

Certified asthma educator

Eligibility Criteria

Age5 Years - 16 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Child is a patient at Erie Family Health Center
  • Child is age 5-16 at the start of the study
  • Child lives with the index caregiver at least 5 days out of the week
  • Child has uncontrolled asthma. This is defined as a score of 1.25 or greater on the Asthma Control Questionnaire, or report of oral corticosteroid use in the past year
  • Family has a working telephone

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Erie Family Health Center

Chicago, Illinois, 60622, United States

Location

Related Publications (4)

  • Lalji R, Koh L, Francis A, Khalid R, Guha C, Johnson DW, Wong G. Patient navigator programmes for children and adolescents with chronic diseases. Cochrane Database Syst Rev. 2024 Oct 9;10(10):CD014688. doi: 10.1002/14651858.CD014688.pub2.

  • Weinstein SM, Pugach O, Rosales G, Mosnaim GS, Orozco K, Pappalardo AA, Martin MA. Psychosocial Moderators and Outcomes of a Randomized Effectiveness Trial for Child Asthma. J Pediatr Psychol. 2021 Jul 20;46(6):673-687. doi: 10.1093/jpepsy/jsab011.

  • Weinstein SM, Pugach O, Rosales G, Mosnaim GS, Walton SM, Martin MA. Family Chaos and Asthma Control. Pediatrics. 2019 Aug;144(2):e20182758. doi: 10.1542/peds.2018-2758. Epub 2019 Jul 9.

  • Mosnaim GS, Weinstein SM, Pugach O, Rosales G, Roy A, Walton S, Martin MA. Design and baseline characteristics of a low-income urban cohort of children with asthma: The Asthma Action at Erie Trial. Contemp Clin Trials. 2019 Apr;79:55-65. doi: 10.1016/j.cct.2019.02.006. Epub 2019 Feb 14.

MeSH Terms

Conditions

Asthma

Interventions

Community Health Workers

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Intervention Hierarchy (Ancestors)

Allied Health PersonnelHealth PersonnelHealth Care Facilities Workforce and Services

Results Point of Contact

Title
Molly A Martin, MD
Organization
University of Illinois Chicago

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

June 5, 2015

First Posted

June 25, 2015

Study Start

April 1, 2015

Primary Completion

March 31, 2020

Study Completion

March 31, 2021

Last Updated

December 9, 2021

Results First Posted

December 9, 2021

Record last verified: 2021-11

Locations