NCT02477683

Brief Summary

The purpose of this study is to collect data to support decisions made by BioFire regarding assay development, panel composition, and intended use for the final FilmArray FI reagent pouch. The study will utilize whole blood and/or plasma obtained from pediatric patients under 3 years of age that present with acute fever.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,514

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2015

Shorter than P25 for all trials

Geographic Reach
1 country

6 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 18, 2015

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 23, 2015

Completed
3 months until next milestone

Study Start

First participant enrolled

October 1, 2015

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2016

Completed
Last Updated

December 21, 2016

Status Verified

December 1, 2016

Enrollment Period

1 year

First QC Date

June 18, 2015

Last Update Submit

December 19, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Utility of multiplexed testing for pathogens in pediatric patients with acute fever

    15 months

Secondary Outcomes (1)

  • Epidemiology of pathogens in pediatric patients with acute fever

    15 Months

Eligibility Criteria

AgeUp to 3 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Pediatric patients under the age of 3 with acute fever.

You may qualify if:

  • under age of 3
  • has fever with no obvious focal infection
  • written informed parental permission

You may not qualify if:

  • parent/legal guardian unable to provide permission
  • participation determined by a physician to be detrimental to patient health

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Emory University

Atlanta, Georgia, 30329, United States

Location

Indiana University School of Medecine

Indianapolis, Indiana, 46202, United States

Location

Children's Mercy Hospitals & Clinics

Kansas City, Missouri, 64108, United States

Location

Washington University in St. Louis

St Louis, Missouri, 63110, United States

Location

Nationwide Children's Hospital

Columbus, Ohio, 43205, United States

Location

Primary Children's Hospital

Salt Lake City, Utah, 84108, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

Plasma and Whole Blood

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 18, 2015

First Posted

June 23, 2015

Study Start

October 1, 2015

Primary Completion

October 1, 2016

Study Completion

October 1, 2016

Last Updated

December 21, 2016

Record last verified: 2016-12

Locations