NCT02476643

Brief Summary

This study aims to test, if a two-week integrative therapy in an internal medicine ward will improve symptoms, disability and quality of life in patients with inflammatory bowel disease or irritable bowel syndrome.a It shall further be tested, if those changes are associated with attitudes and experiences towards complementary and alternative medicine, anxiety, depression and stress perception as well as body awareness and responsiveness.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2015

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 12, 2015

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 19, 2015

Completed
3 months until next milestone

Study Start

First participant enrolled

October 1, 2015

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2018

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2018

Completed
Last Updated

May 2, 2018

Status Verified

April 1, 2018

Enrollment Period

2.5 years

First QC Date

June 12, 2015

Last Update Submit

April 30, 2018

Conditions

Outcome Measures

Primary Outcomes (3)

  • Symptoms Severity IBS-SSS

    Symptoms Severity assessed by Irritable Bowel Syndrome Symptom Severity Score (IBS-SSS) (Francis, 1997)

    2 weeks

  • Symptoms Severity CAI

    Symptoms Severity assessed by Clinical Activity Index (CAI) (Rachmilewitz 1989)

    2 weeks

  • Symptoms Severity CDAI

    Symptoms Severity assessed by Crohn Disease Activity Index (CDAI)

    2 weeks

Secondary Outcomes (14)

  • Symptoms Severity IBS-SSS

    24 weeks

  • Symptoms Severity CAI

    24 weeks

  • Symptoms Severity CDAI

    24 weeks

  • Disability MYMOP

    2 weeks

  • Disability MYMOP

    24 weeks

  • +9 more secondary outcomes

Study Arms (1)

Integrative Therapy

This group receives and integrative therapy at the Department of Internal and Integrative Medicine, i.e. a combination of conventional diagnostic and therapeutic interventions with specific naturopathic, and complementary medicine approaches, and physical therapy. Patients are admitted to the hospital ward for 14 days.

Other: Integrative Therapy

Interventions

This group receives an integrative therapy at the Department of Internal and Integrative Medicine, i.e. a combination of conventional diagnostic and therapeutic interventions with specific naturopathic, and complementary medicine approaches, and physical therapy.

Integrative Therapy

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

100 patients with Inflammentory Bowel Disease admitted to the Department of Internal and Integrative Medicine. 100 patients with Irritable Bowel Syndrome admitted to the Department of Internal and Integrative Medicine.

You may qualify if:

  • years or older
  • diagnosed with Irritable Bowel Syndrome (IBS) or Inflammatory Bowel Disease (IBD)
  • written informed consent

You may not qualify if:

  • participation in other clinical studies

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Internal and Integrative Medicine, Kliniken Essen-Mitte

Essen, 45276, Germany

Location

MeSH Terms

Conditions

Crohn DiseaseColitis, UlcerativeIrritable Bowel Syndrome

Condition Hierarchy (Ancestors)

Inflammatory Bowel DiseasesGastroenteritisGastrointestinal DiseasesDigestive System DiseasesIntestinal DiseasesColitisColonic DiseasesColonic Diseases, Functional

Study Officials

  • Gustav Dobos, Prof, MD

    Department of Internal and Integrative Medicine, Kliniken Essen-Mitte

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

June 12, 2015

First Posted

June 19, 2015

Study Start

October 1, 2015

Primary Completion

April 1, 2018

Study Completion

December 1, 2018

Last Updated

May 2, 2018

Record last verified: 2018-04

Locations